Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAMBP | O95630 | 5/20 | 0.55 |
| ▸ | PSMD14 | O00487 | 4/20 | 0.55 |
| ▸ | COPS5 | Q92905 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | MMP13 | P45452 | 1/20 | 0.48 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.47 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.47 |
| ▸ | HPGDS | O60760 | 1/20 | 0.46 |
| ▸ | AKT1 | P31749 | 2/20 | 0.46 |
| ▸ | AKT2 | P31751 | 1/20 | 0.46 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.46 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 2/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.45 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.45 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.45 |
| ▸ | PRKCG | P05129 | 1/20 | 0.45 |
| ▸ | PRKACA | P17612 | 1/20 | 0.45 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL619835 | 0.82 | HTT (0.49) | — | |
| SCHEMBL253871 | 0.81 | HPGDS (0.60) | STAMBPPSMD14COPS5HPGDSNAMPT | |
| SCHEMBL246648 | 0.80 | MMP13 (0.74) | TSHRHDAC6MMP13AKT1NAMPT | |
| SCHEMBL252287 | 0.79 | STAMBP (0.51) | STAMBPPSMD14COPS5NAMPT | |
| SCHEMBL14082503 | 0.77 | ROCK2 (0.74) | HDAC6MMP13SCN2ASCN10AHPGDS | |
| SCHEMBL14082493 | 0.77 | MMP13 (0.79) | TSHRHDAC6MMP13AKT1NAMPT | |
| SCHEMBL253899 | 0.76 | PSMD14 (0.46) | STAMBPPSMD14COPS5TSHRHPGDS | |
| SCHEMBL255348 | 0.76 | NAMPT (0.52) | STAMBPPSMD14COPS5NAMPTMAPK1 | |
| SCHEMBL14082585 | 0.76 | ALDH1A1 (0.69) | TSHRMMP13AKT1NAMPTROCK2 | |
| SCHEMBL253234 | 0.75 | PSMD14 (0.50) | STAMBPPSMD14COPS5TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2401275-A1 | NOVEL BRONCHODILATING DIAZAHETEROARYLS | Respiratorius AB (SE) | 2012-01-04 | — | — | EP | claimed |