Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.45 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.45 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.45 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | LIPE | Q05469 | 2/20 | 0.45 |
| ▸ | NAMPT | P43490 | 2/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP14 | P50281 | 1/20 | 0.44 |
| ▸ | KIF11 | P52732 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9779140 | 0.86 | MMP9 (0.56) | BCHEACHEFFAR4PKMNAMPT | |
| SCHEMBL10983944 | 0.85 | HTR6 (0.54) | HSD11B1BCHEACHEFFAR4ABCC9 | |
| SCHEMBL28160035 | 0.84 | KIF11 (0.46) | HSD11B1BCHEACHESOS1FFAR4 | |
| SCHEMBL255560 | 0.83 | GPR3 (0.52) | HSD11B1GAAKIF11 | |
| SCHEMBL7937278 | 0.83 | PKM (0.59) | HSD11B1BCHEACHEFFAR4GAA | |
| SCHEMBL10985063 | 0.83 | ALDH1A1 (0.59) | BCHEACHEFFAR4PTGDR2PKM | |
| SCHEMBL7929090 | 0.83 | SOS1 (0.46) | HSD11B1SOS1GAAABCC9ABCC8 | |
| SCHEMBL10988447 | 0.83 | BCHE (0.66) | HSD11B1BCHEACHEFFAR4GAA | |
| SCHEMBL7570513 | 0.80 | FFAR4 (0.64) | FFAR4KIF11 | |
| SCHEMBL14138146 | 0.79 | SOS1 (0.70) | HSD11B1SOS1FFAR4PKMMMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242654-B1 | REACTING A PHENOLATE COMPOUND WITH AN ORGANIC FLUORINATING AGENT TO PREPARE A FLUORINE SUBSTITUTED AROMATIC COMPOUND | MITSUI CHEMICALS, INC. (JP) | 2001-06-05 | — | — | US | disclosed |
| EP-1013629-A1 | Preparation process of fluorine subsituted aromatic compound | Mitsui Chemicals, Inc. (JP) | 2000-06-28 | — | — | EP | disclosed |