Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 1/20 | 0.50 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.50 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.50 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 3/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25075207 | 0.91 | GNAI3 (0.38) | CARM1PRMT6PRMT1PRMT8POLB | |
| SCHEMBL20234635 | 0.83 | CARM1 (0.65) | CARM1PRMT6PRMT1PRMT8POLB | |
| SCHEMBL26267339 | 0.83 | OPRM1 (0.34) | CARM1PRMT6PRMT1PRMT8POLB | |
| SCHEMBL25075429 | 0.82 | ALDH1A1 (0.52) | POLBHTT | |
| SCHEMBL26494066 | 0.82 | GNAO1 (0.44) | SIGMAR1 | |
| SCHEMBL4762635 | 0.82 | DRD2 (0.46) | — | |
| SCHEMBL25075441 | 0.82 | PRMT6 (0.33) | CARM1PRMT6PRMT1PRMT8POLB | |
| SCHEMBL25075222 | 0.81 | CARM1 (0.37) | CARM1PRMT6POLBHTT | |
| SCHEMBL25444765 | 0.81 | GNAO1 (0.34) | CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL26445316 | 0.79 | DAO (0.41) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023083194-A1 | WEE1 PROTEIN KINASE DEGRADATION AGENT AND USE THEREOF | 杭州格博生物医药有限公司 | 2023-05-19 | — | — | WO | disclosed |