Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | RAB9A | P51151 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25564759 | 0.85 | MAPK14 (0.58) | RAB9ANPC1MEN1KMT2AFLT3 | |
| SCHEMBL25567247 | 0.78 | MAPK14 (0.59) | ALDH1A1KDRFLT3 | |
| SCHEMBL25567722 | 0.76 | MAPK14 (0.46) | RAB9ANPC1MEN1KMT2AKDR | |
| SCHEMBL25566546 | 0.76 | TRPV1 (0.57) | RAB9ASMN1; SMN2NPC1MEN1KMT2A | |
| SCHEMBL25566088 | 0.76 | MAPK14 (0.51) | EPHX2 | |
| SCHEMBL3662896 | 0.76 | CRBN (0.52) | SMN1; SMN2L3MBTL1CYP1A2POLBCRBN | |
| SCHEMBL25567190 | 0.75 | EGFR (0.49) | RAB9ANPC1MEN1KMT2AFLT3 | |
| SCHEMBL25567562 | 0.74 | HPGD (0.47) | RAB9ANPC1MEN1KMT2AFLT3 | |
| Hydrochloric Acid SCHEMBL1188418 | 0.74 | RAB9A (0.57) | ALDH1A1RAB9ASMN1; SMN2NPC1L3MBTL1 | |
| SCHEMBL396156 | 0.73 | DDX3X (0.59) | ALDH1A1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023078207-A1 | 6-POSITION-SUBSTITUTED INDOLINONE DERIVATIVE, PREPARATION METHOD THEREFOR, AND MEDICAL USE THEREOF | 南京中医药大学 | 2023-05-11 | — | — | WO | disclosed |