Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 3/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 12/20 | 0.45 |
| ▸ | CSF1R | P07333 | 1/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.41 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.41 |
| ▸ | BRAF | P15056 | 1/20 | 0.41 |
| ▸ | RAF1 | P04049 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25567247 | 0.89 | MAPK14 (0.59) | MAPK14TRPV1CSF1RNTRK1NTRK3 | |
| SCHEMBL25566378 | 0.81 | CSF1R (0.52) | EPHX2TRPV1CSF1R | |
| SCHEMBL25567264 | 0.78 | MAPK14 (0.45) | MAPK14TRPV1CSF1RNTRK1NTRK3 | |
| SCHEMBL25566598 | 0.76 | KDR (0.51) | EPHX2TRPV1CSF1RBRAF | |
| SCHEMBL25566268 | 0.76 | KDR (0.65) | TRPV1 | |
| SCHEMBL25565993 | 0.76 | ALDH1A1 (0.58) | EPHX2 | |
| SCHEMBL25564759 | 0.75 | MAPK14 (0.58) | MAPK14CSF1RRAF1 | |
| SCHEMBL25566713 | 0.73 | CSF1R (0.52) | EPHX2TRPV1CSF1RBRAF | |
| SCHEMBL3598229 | 0.73 | KIF11 (0.68) | EPHX2TRPV1NTRK1NTRK3 | |
| SCHEMBL25567411 | 0.73 | ALDH1A1 (0.49) | MAPK14CSF1RNTRK1NTRK3NTRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023078207-A1 | 6-POSITION-SUBSTITUTED INDOLINONE DERIVATIVE, PREPARATION METHOD THEREFOR, AND MEDICAL USE THEREOF | 南京中医药大学 | 2023-05-11 | — | — | WO | disclosed |