Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 2/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | FABP4 | P15090 | 1/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5698446 | 0.82 | MYC (0.42) | MYCELANETSHRSMN1; SMN2TTR | |
| SCHEMBL8983185 | 0.82 | MYC (0.42) | MYCELANETSHRSMN1; SMN2TTR | |
| SCHEMBL4962913 | 0.80 | MYC (0.41) | MYCELANETSHRSMN1; SMN2TTR | |
| SCHEMBL28521154 | 0.80 | MYC (0.41) | MYCELANETSHRSMN1; SMN2TTR | |
| SCHEMBL6160456 | 0.80 | SMN1; SMN2 (0.46) | MYCELANETSHRSMN1; SMN2TTR | |
| SCHEMBL286480 | 0.78 | HTR6 (0.60) | MYCTSHRHTR6FABP4KMT2A | |
| SCHEMBL14635879 | 0.78 | MYC (0.40) | MYCELANETSHRSMN1; SMN2TTR | |
| SCHEMBL10908439 | 0.78 | ELANE (0.44) | MYCELANETSHRSMN1; SMN2TTR | |
| SCHEMBL22442051 | 0.78 | MYC (0.40) | MYCELANETSHRSMN1; SMN2TTR | |
| SCHEMBL8363338 | 0.78 | MYC (0.44) | MYCELANETSHRSMN1; SMN2TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10844088-B2 | Process for the preparation of estetrol | ESTETRA SPRL (BE) | 2020-11-24 | — | — | US | claimed |
| WO-2020130080-A1 | METHOD FOR PRODUCING P-QUINONES | 学校法人立命館 | 2020-06-25 | — | — | WO | claimed |
| EP-2755989-B1 | METHOD FOR PREPARATION OF BETULINIC ACID | STORA ENSO OYJ (FI) | 2018-01-31 | — | — | EP | claimed |
| US-20170369521-A1 | PROCESS FOR THE PREPARATION OF ESTETROL | DONESTA BIOSCIENCE B.V. (NL) | 2017-12-28 | — | — | US | claimed |
| EP-2734536-B1 | PROCESS FOR THE PREPARATION OF ESTETROL | DONESTA BIOSCIENCE B V (NL) | 2016-09-28 | — | — | EP | claimed |
| US-20140235882-A1 | PROCESS FOR THE PREPARATION OF ESTETROL | Pantarhei Biocience B.V. | 2014-08-21 | — | — | US | claimed |
| EP-2734536-A1 | PROCESS FOR THE PREPARATION OF ESTETROL | Pantarhei Bioscience B.V. (NL) | 2014-05-28 | — | — | EP | claimed |
| CN-103781795-A | Process for the preparation of estetrol | PANTARHEI BIOSCIENCE BV | 2014-05-07 | — | — | CN | claimed |
| WO-2013157018-A1 | A PROCESS FOR THE PREPARATION OF THE CORE STRUCTURE IN QUINOLONE AND NAPTHYRIDONE CLASS OF ANTIBIOTICS | INDIAN INSTITUTE OF TECHNOLOGY MADRAS (IN) | 2013-10-24 | — | — | WO | claimed |
| WO-2013012328-A1 | PROCESS FOR THE PREPARATION OF ESTETROL | PANTARHEI BIOSCIENCE B.V. (NL) | 2013-01-24 | — | — | WO | claimed |
| EP-2383279-A1 | Process for the preparation of estetrol | Pantarhei Bioscience B.V. (NL) | 2011-11-02 | — | — | EP | claimed |
| US-12617952-B1 | Self-ameliorate-fissure-responsive pod system for alkyd-polyester aircraft runway paint | UNIVERSITY OF TABUK (SA) | 2026-05-05 | — | — | US | disclosed |
| EP-4402138-B1 | 3-PHENOXYAZETIDIN-1-YL-HETEROARYL PYRROLIDINE DERIVATIVES AND THE USE THEREOF AS MEDICAMENT | BOEHRINGER INGELHEIM INT (DE) | 2025-08-27 | — | — | EP | disclosed |
| US-20240389593-A1 | HETEROCYCLIC COMPOUND AND USE THEREOF | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2024-11-28 | — | — | US | disclosed |
| US-12115157-B2 | 3-phenoxyazetidin-1-yl-heteroaryl pyrrolidine derivatives and the use thereof as medicament | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2024-10-15 | — | — | US | disclosed |
| WO-2013012328-A1 | PROCESS FOR THE PREPARATION OF ESTETROL | PANTARHEI BIOSCIENCE B.V. (NL) | 2013-01-24 | — | — | WO | disclosed |
| EP-2085373-B1 | METHOD FOR PRODUCING CARBONYL COMPOUND AN PRO-OXIDANT USED FOR PRODUCTION OF CARBONYL COMPOUND | UNIV NAGOYA NAT UNIV CORP (JP) | 2013-01-16 | — | — | EP | disclosed |
| EP-2383279-A1 | Process for the preparation of estetrol | Pantarhei Bioscience B.V. (NL) | 2011-11-02 | — | — | EP | disclosed |
| CN-1071540-C | Stabilization of aqueous 3-isothiazolone solutions | ROHM & HAAS (US) | 2001-09-26 | — | — | CN | disclosed |
| CN-1140542-A | Stabilization of aqueous 3-isothiazolone solutions | ROHM & HAAS (US) | 1997-01-22 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170369521-A1 | PROCESS FOR THE PREPARATION OF ESTETROL | HSD17B11, CYP19A1, SULT1A1 | MYC 3545/4885ELANE 593/4885TSHR 689/4885 |
| US-12617952-B1 | Self-ameliorate-fissure-responsive pod system for alkyd-polyester aircraft runway paint | PARG, PLOD3, PARN | MYC 1869/4885ELANE 4046/4885TSHR 297/4885 |
| US-12115157-B2 | 3-phenoxyazetidin-1-yl-heteroaryl pyrrolidine derivatives and the use thereof as medicament | GPR52, GPR88, GPR68 | MYC 3897/4885ELANE 4787/4885TSHR 1815/4885 |
| US-10844088-B2 | Process for the preparation of estetrol | HSD17B11, CYP19A1, SULT1A1 | MYC 3871/4885ELANE 520/4885TSHR 636/4885 |
| US-20140235882-A1 | PROCESS FOR THE PREPARATION OF ESTETROL | CYP19A1, HSD17B11, SULT1A1 | MYC 3906/4885ELANE 483/4885TSHR 1317/4885 |
| US-20240389593-A1 | HETEROCYCLIC COMPOUND AND USE THEREOF | C1S, C3AR1, CBR3 | MYC 2353/4885ELANE 3175/4885TSHR 423/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.