Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 8/20 | 0.35 |
| ▸ | CNR1 | P21554 | 6/20 | 0.35 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL2563941 | 1.00 | ALDH1A1 (0.39) | ALDH1A1CA4CA1CA9CNR2 | |
| Sorbic Acid SCHEMBL3641 | 0.97 | — | — | |
| Sorbic Acid SCHEMBL29573362 | 0.97 | CA4 (0.40) | ALDH1A1CA4CA1CA9CNR2 | |
| Sorbic Acid SCHEMBL3640 | 0.97 | — | — | |
| Sorbic Acid SCHEMBL929156 | 0.97 | CA4 (0.40) | ALDH1A1CA4CA1CA9CNR2 | |
| Sorbic Acid SCHEMBL929158 | 0.97 | CA4 (0.40) | ALDH1A1CA4CA1CA9CNR2 | |
| Sorbic Acid SCHEMBL7567295 | 0.95 | CA4 (0.38) | ALDH1A1CA4CA1CA9CNR2 | |
| SCHEMBL416205 | 0.95 | ALDH1A1 (0.39) | ALDH1A1CA4CA1CA9CNR2 | |
| Sorbic Acid SCHEMBL5328357 | 0.95 | CA4 (0.43) | ALDH1A1CA4CA1CA9CNR2 | |
| Sorbic Acid SCHEMBL30195487 | 0.95 | CA4 (0.43) | ALDH1A1CA4CA1CA9CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3041459-B1 | COMPOSITIONS USEFUL IN THE PREVENTION OR TREATMENT OF SKIN CANCER | GIULIANI SPA (IT) | 2019-04-03 | — | — | EP | claimed |
| EP-3041459-A1 | COMPOSITIONS USEFUL IN THE PREVENTION OR TREATMENT OF SKIN CANCER | Giuliani S.p.A. (IT) | 2016-07-13 | — | — | EP | claimed |
| WO-2015033276-A1 | COMPOSITIONS USEFUL IN THE PREVENTION OR TREATMENT OF SKIN CANCER | GIULIANI S.P.A. (IT) | 2015-03-12 | — | — | WO | claimed |
| EP-3490680-B1 | TOPICAL COSMETIC COMPOSITION FOR RESTRUCTURING AND PROTECTING HAIR AND SCALP, AND USES THEREOF | KEMON S P A (IT) | 2025-11-19 | — | — | EP | disclosed |
| EP-4464307-A1 | COSMETIC COMPOSITION AND METHODS OF MAKING THE SAME | MPLUS COSMETICS S.R.L. (IT) | 2024-11-20 | — | — | EP | disclosed |
| US-20240374498-A1 | COSMETIC COMPOSITION AND METHODS OF MAKING THE SAME | MPLUS COSMETICS S.R.L. (IT) | 2024-11-14 | — | — | US | disclosed |
| US-9289405-B2 | Compounds provided with antioxidant activity against free radicals, and pharmaceutical and cosmetic compositions containing them | GIULIANI S.P.A (IT) | 2016-03-22 | — | — | US | disclosed |
| EP-2560632-B1 | COMPOUNDS PROVIDED WITH ANTIOXIDANT ACTIVITY AGAINST FREE RADICALS, AND COSMETIC COMPOSITIONS CONTAINING THEM | GIULIANI SPA (IT) | 2014-10-29 | — | — | EP | disclosed |
| EP-2560632-A1 | COMPOUNDS PROVIDED WITH ANTIOXIDANT ACTIVITY AGAINST FREE RADICALS, AND PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING THEM | Giuliani S.p.A. (IT) | 2013-02-27 | — | — | EP | disclosed |
| US-20130046017-A1 | COMPOUNDS PROVIDED WITH ANTIOXIDANT ACTIVITY AGAINST FREE RADICALS, AND PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING THEM | GIULIANI S.P.A. (IT) | 2013-02-21 | — | — | US | disclosed |
| WO-2011132177-A1 | COMPOUNDS PROVIDED WITH ANTIOXIDANT ACTIVITY AGAINST FREE RADICALS, AND PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING THEM | GIULIANI S.P.A. (IT) | 2011-10-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130046017-A1 | COMPOUNDS PROVIDED WITH ANTIOXIDANT ACTIVITY AGAINST FREE RADICALS, AND PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING THEM | LPO, CAT, TYR | ALDH1A1 197/4885CA4 1132/4885CA1 3165/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.