SCHEMBL25640472 — predicted protein targets

Predicted protein targets (top 15)

	gene	UniProt	supporting neighbours	confidence
▸	KMT2A	Q03164	3/20	0.41

▸	MAPT	P10636	2/20	0.41

▸	ALDH1A1	P00352	1/20	0.41

▸	MEN1	O00255	1/20	0.41

▸	ATM	Q13315	1/20	0.39

▸	KCNJ1	P48048	8/20	0.38

▸	ABL1	P00519	2/20	0.37

▸	RIN1	Q13671	2/20	0.37

▸	ALPL	P05186	1/20	0.37

▸	ALPI	P09923	1/20	0.37

▸	ALPG	P10696	1/20	0.37

▸	L3MBTL1	Q9Y468	1/20	0.36

▸	TLR9	Q9NR96	1/20	0.36

▸	TLR8	Q9NR97	1/20	0.36

▸	TLR7	Q9NYK1	1/20	0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL31677627	0.89	KCNJ1 (0.39)	KCNJ1L3MBTL1TLR9TLR8TLR7
SCHEMBL25640470	0.89	KCNJ1 (0.39)	KCNJ1L3MBTL1TLR9TLR8TLR7
SCHEMBL25640474	0.81	PKM (0.41)	KMT2AALDH1A1MEN1KCNJ1
SCHEMBL25640475	0.81	CHRNB2 (0.44)	KMT2AMAPTALDH1A1
SCHEMBL25478882	0.80	LTA4H (0.39)	ALDH1A1KCNJ1
SCHEMBL25640507	0.80	HRH3 (0.40)	KMT2AMEN1
SCHEMBL25640513	0.80	TACR1 (0.40)	ALDH1A1
SCHEMBL25640471	0.79	TACR1 (0.44)	—
SCHEMBL25268635	0.78	TRPV6 (0.44)	KCNJ1TLR9TLR8TLR7
SCHEMBL30414542	0.78	TRPV6 (0.44)	KCNJ1TLR9TLR8TLR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2023104043-A1	ANTI-APOPTOTIC PROTEIN BCL-2 INHIBITOR, PHARMACEUTICAL COMPOSITION AND USES THEREOF	杭州和正医药有限公司	2023-06-15	—	—	WO	disclosed