Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORB | Q92753 | 17/20 | 0.79 |
| ▸ | RORC | P51449 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL257269 | 0.83 | RORB (0.60) | RORBRORCALDH1A1HSD17B10CYP1A2 | |
| SCHEMBL27653923 | 0.82 | ALDH1A1 (0.64) | RORBRORCALDH1A1HSD17B10CYP1A2 | |
| SCHEMBL257375 | 0.80 | RORB (0.60) | RORBRORCALDH1A1HSD17B10CYP1A2 | |
| SCHEMBL257260 | 0.80 | RORB (0.60) | RORBRORCALDH1A1HSD17B10CYP1A2 | |
| SCHEMBL257608 | 0.80 | RORB (0.83) | RORBRORCALDH1A1HSD17B10CYP1A2 | |
| SCHEMBL4879040 | 0.78 | FBP1 (0.61) | RORB | |
| SCHEMBL165773 | 0.78 | ADORA3 (0.61) | RORBALDH1A1HSD17B10CYP1A2CYP2D6 | |
| SCHEMBL257433 | 0.77 | RORB (0.72) | RORBRORCALDH1A1HSD17B10 | |
| SCHEMBL2762916 | 0.76 | ALDH1A1 (0.64) | RORBALDH1A1HSD17B10CYP1A2CYP2D6 | |
| SCHEMBL257142 | 0.76 | RORB (1.00) | RORBRORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012027965-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2012-03-08 | — | — | WO | disclosed |
| WO-2012027965-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2012-03-08 | — | — | WO | disclosed |