Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORB | Q92753 | 15/20 | 0.60 |
| ▸ | RORC | P51449 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL256653 | 0.90 | RORB (0.59) | RORBRORCALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL257434 | 0.86 | RORB (0.79) | RORBRORC | |
| SCHEMBL27653923 | 0.85 | ALDH1A1 (0.64) | RORBRORCALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL257375 | 0.83 | RORB (0.60) | RORBRORCALDH1A1HSD17B10CYP1A2 | |
| SCHEMBL257608 | 0.83 | RORB (0.83) | RORBRORCALDH1A1HSD17B10CYP1A2 | |
| SCHEMBL257260 | 0.83 | RORB (0.60) | RORBRORCALDH1A1HSD17B10CYP1A2 | |
| SCHEMBL256651 | 0.83 | RORB (0.79) | RORBRORCALDH1A1HSD17B10CYP1A2 | |
| SCHEMBL165773 | 0.81 | ADORA3 (0.61) | RORBALDH1A1HSD17B10SMN1; SMN2CYP1A2 | |
| SCHEMBL1255464 | 0.81 | MEN1 (0.50) | RORBRORCALDH1A1HSD17B10NPC1 | |
| SCHEMBL257433 | 0.80 | RORB (0.72) | RORBRORCALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012027965-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2012-03-08 | — | — | WO | disclosed |