Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.56 |
| ▸ | IL1RN | P18510 | 1/20 | 0.55 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.55 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.55 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | HTR2C | P28335 | 1/20 | 0.54 |
| ▸ | HTR2B | P41595 | 1/20 | 0.54 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7854392 | 0.89 | TSHR (0.70) | TSHRRXFP1KEAP1MEN1KMT2A | |
| SCHEMBL6760868 | 0.87 | RECQL (0.57) | RECQLALDH1A1SMN1; SMN2TSHRIL1RN | |
| SCHEMBL7090449 | 0.85 | CA1 (0.64) | TSHRRXFP1KEAP1MEN1KMT2A | |
| SCHEMBL3072539 | 0.85 | LMNA (0.70) | ALDH1A1SMN1; SMN2TSHRKEAP1 | |
| SCHEMBL2067538 | 0.85 | ALDH1A1 (0.68) | RECQLALDH1A1SMN1; SMN2IL1RNKEAP1 | |
| SCHEMBL6394653 | 0.82 | GRM4 (0.57) | TSHRKEAP1MEN1KMT2AGRM4 | |
| SCHEMBL5801171 | 0.82 | LMNA (0.61) | TSHRKEAP1MEN1KMT2A | |
| SCHEMBL5480533 | 0.81 | POLB (0.62) | ALDH1A1SMN1; SMN2TSHRMEN1KMT2A | |
| SCHEMBL21893366 | 0.81 | CA2 (0.62) | ALDH1A1SMN1; SMN2TSHRRXFP1MEN1 | |
| SCHEMBL398719 | 0.81 | KDM4E (0.71) | ALDH1A1TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2382191-A1 | NOVEL BENZENESULFONAMIDES AS CALCIUM CHANNEL BLOCKERS | Abbott Laboratories, Inc. (US) | 2011-11-02 | — | — | EP | claimed |
| CN-104136435-A | BROMODOMAIN INHIBITORS | ABBVIE INC | 2014-11-05 | — | — | CN | disclosed |
| EP-2382191-A1 | NOVEL BENZENESULFONAMIDES AS CALCIUM CHANNEL BLOCKERS | Abbott Laboratories, Inc. (US) | 2011-11-02 | — | — | EP | disclosed |
| US-20030162817-A1 | Pentafluorobenzenesulfonamides and analogs | TULARIK INC. | 2003-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030162817-A1 | Pentafluorobenzenesulfonamides and analogs | FGFR1, FPR1, FGF1 | RECQL 4221/4885ALDH1A1 1192/4885SMN1; SMN2 4509/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.