Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12735971 | 0.89 | TSHR (0.43) | ARTSHRMAPK1MAPTTDP1 | |
| SCHEMBL193998 | 0.88 | AR (0.46) | ARTSHRMAPTTDP1POLB | |
| SCHEMBL2741333 | 0.85 | TSHR (0.41) | ARTSHRMAPK1MAPTTDP1 | |
| SCHEMBL2741729 | 0.82 | TSHR (0.46) | ARTSHRMAPK1MAPTTDP1 | |
| SCHEMBL12735959 | 0.80 | MAPT (0.43) | ARTSHRMAPTTDP1POLB | |
| SCHEMBL472133 | 0.79 | CA12 (0.43) | MAPTALDH1A1HTTLMNAMEN1 | |
| SCHEMBL2741078 | 0.77 | MAPT (0.41) | ARTSHRMAPTTDP1POLB | |
| SCHEMBL194650 | 0.75 | VDR (0.47) | ARTSHRMAPTTDP1ALDH1A1 | |
| SCHEMBL11385028 | 0.74 | ALDH1A1 (0.49) | ARTSHRMAPK1MAPTPOLB | |
| SCHEMBL17257811 | 0.73 | ALOX5 (0.44) | MAPTTDP1POLBHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8476379-B2 | Silphenylene skeleton-containing silicone type polymer and method for manufacturing the same | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2013-07-02 | — | — | US | disclosed |
| EP-2386591-B1 | Silphenylene skeleton-containing silicone type polymer and method for manufacturing the same | SHINETSU CHEMICAL CO (JP) | 2013-04-17 | — | — | EP | disclosed |
| US-8378148-B2 | Alcoholic hydroxyl-containing compounds and making method | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2013-02-19 | — | — | US | disclosed |
| US-8378148-B2 | Alcoholic hydroxyl-containing compounds and making method | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2013-02-19 | — | — | US | disclosed |
| EP-2316810-B1 | Alcoholic hydroxyl-containing compounds and making method | SHINETSU CHEMICAL CO (JP) | 2012-01-04 | — | — | EP | disclosed |
| EP-2386591-A2 | Novel silphenylene skeleton-containing silicon type polymer and method for manufacturing the same | Shin-Etsu Chemical Co., Ltd. (JP) | 2011-11-16 | — | — | EP | disclosed |
| US-20110275768-A1 | NOVEL SILPHENYLENE SKELETON-CONTAINING SILICONE TYPE POLYMER AND METHOD FOR MANUFACTURING THE SAME | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2011-11-10 | — | — | US | disclosed |
| EP-2316810-A1 | Alcoholic hydroxyl-containing compounds and making method | Shin-Etsu Chemical Co., Ltd. (JP) | 2011-05-04 | — | — | EP | disclosed |
| US-20110082321-A1 | ALCOHOLIC HYDROXYL-CONTAINING COMPOUNDS AND MAKING METHOD | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2011-04-07 | — | — | US | disclosed |
| US-20110082321-A1 | ALCOHOLIC HYDROXYL-CONTAINING COMPOUNDS AND MAKING METHOD | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2011-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110082321-A1 | ALCOHOLIC HYDROXYL-CONTAINING COMPOUNDS AND MAKING METHOD | ADH1A, ADH1C, ADH5 | AR 121/4885TSHR 2707/4885MAPK1 4359/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.