Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORB | Q92753 | 16/20 | 0.59 |
| ▸ | RORC | P51449 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL257269 | 0.90 | RORB (0.60) | RORBRORCMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL257437 | 0.87 | RORB (0.76) | RORBRORCPOLBMAPTMEN1 | |
| SCHEMBL257434 | 0.87 | RORB (0.79) | RORBRORC | |
| SCHEMBL178218 | 0.82 | ADORA3 (0.60) | RORBRORCPOLBMAPTMEN1 | |
| SCHEMBL257438 | 0.80 | ADORA3 (0.54) | RORBRORCPOLBMAPTMEN1 | |
| SCHEMBL257608 | 0.79 | RORB (0.83) | RORBRORCPOLBMAPTALDH1A1 | |
| SCHEMBL257616 | 0.79 | ADORA3 (0.64) | RORBMAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL178204 | 0.78 | CDK5 (0.58) | RORBRORCPOLB | |
| SCHEMBL2491634 | 0.77 | POLB (0.55) | RORBPOLBMAPTMEN1ALDH1A1 | |
| SCHEMBL1255464 | 0.77 | MEN1 (0.50) | RORBRORCPOLBMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012027965-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2012-03-08 | — | — | WO | disclosed |