Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 2/20 | 0.41 |
| ▸ | FPR2 | P25090 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MLYCD | O95822 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.38 |
| ▸ | ALPL | P05186 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CFTR | P13569 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25745901 | 0.81 | SMN1; SMN2 (0.42) | LMNANAMPTSMN1; SMN2 | |
| SCHEMBL25745885 | 0.75 | NAMPT (0.48) | LMNAGAAKMT2AHSD17B10NAMPT | |
| SCHEMBL25745966 | 0.73 | EGLN2 (0.39) | FPR2BACE1ALDH1A1 | |
| SCHEMBL31348094 | 0.68 | ALDH1A1 (0.43) | KMT2ABACE1ALDH1A1SMN1; SMN2 | |
| SCHEMBL19435882 | 0.67 | BACE1 (0.41) | FPR2BACE1ALDH1A1SMN1; SMN2 | |
| SCHEMBL14022267 | 0.64 | PRKCI (0.48) | DYRK1AGAAKMT2AHSD17B10MLYCD | |
| SCHEMBL29824281 | 0.64 | LMNA (0.62) | LMNAGAAKMT2AHSD17B10TAS1R3 | |
| SCHEMBL17641571 | 0.63 | SYK (0.43) | NAMPT | |
| SCHEMBL30445348 | 0.63 | HPGDS (0.39) | DYRK1AFPR2MLYCD | |
| SCHEMBL161702 | 0.62 | KMT2A (0.45) | DYRK1AGAAKMT2AHSD17B10MLYCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3781554-B1 | 2,6-DIAMINO-3,4-DIHYDROPYRIMIDIN-4-ONE DERIVATIVES AND USE THEREOF IN THERAPY | THOMAS HELLEDAYS STIFTELSE FOER MEDICINSK FORSKNING (SE) | 2023-06-28 | — | — | EP | disclosed |