Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2681471 | 0.91 | KDM4E (0.38) | KMT2AMEN1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL25760294 | 0.90 | RAB9A (0.40) | KMT2AMEN1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL21751286 | 0.89 | PIK3CA (0.38) | KMT2AMEN1SMN1; SMN2PTGS2ADORA2A | |
| SCHEMBL21751391 | 0.86 | MAOA (0.33) | KMT2AMEN1SMN1; SMN2ADORA2AADORA2B | |
| SCHEMBL30800183 | 0.86 | MAOA (0.33) | KMT2AMEN1SMN1; SMN2ADORA2AADORA2B | |
| SCHEMBL25760166 | 0.85 | THRB (0.38) | KMT2AMEN1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL20543611 | 0.85 | THRB (0.42) | KMT2AMEN1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL5555425 | 0.84 | KDM4E (0.35) | RAB9ASMN1; SMN2L3MBTL1PTGS2ADORA2A | |
| SCHEMBL25760289 | 0.84 | KMT2A (0.36) | KMT2AMEN1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL25760270 | 0.84 | ADORA2B (0.38) | KMT2AMEN1RAB9ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11691976-B2 | Coelenterazine analogues | PROMEGA CORPORATION (US) | 2023-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11691976-B2 | Coelenterazine analogues | GLB1, SI, TCF7L2 | KMT2A 2122/4885MEN1 1826/4885RAB9A 1793/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.