Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | ALKBH3 | Q96Q83 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.34 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25760294 | 0.95 | RAB9A (0.40) | THRBRAB9AKMT2ANPC1MEN1 | |
| SCHEMBL20543611 | 0.92 | THRB (0.42) | THRBRAB9AKMT2ANPC1MEN1 | |
| SCHEMBL25760275 | 0.90 | THRB (0.36) | THRBRAB9AKMT2ANPC1MEN1 | |
| SCHEMBL25760164 | 0.90 | ADORA3 (0.37) | PDE3BPDE3ACCNE2CCNE1CDK2 | |
| SCHEMBL25760289 | 0.90 | KMT2A (0.36) | THRBRAB9AKMT2ANPC1MEN1 | |
| SCHEMBL25760298 | 0.89 | MAPT (0.46) | KMT2AMEN1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL25760179 | 0.89 | CASR (0.39) | THRBRAB9AKMT2ANR3C1ALDH1A1 | |
| SCHEMBL25760304 | 0.88 | KDM4E (0.44) | RAB9AKMT2ANPC1MEN1SMN1; SMN2 | |
| SCHEMBL25760310 | 0.87 | RAB9A (0.36) | THRBRAB9AKMT2ANPC1MEN1 | |
| SCHEMBL25760270 | 0.87 | ADORA2B (0.38) | RAB9AKMT2ANPC1MEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11691976-B2 | Coelenterazine analogues | PROMEGA CORPORATION (US) | 2023-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11691976-B2 | Coelenterazine analogues | GLB1, SI, TCF7L2 | THRB 811/4885RAB9A 1793/4885KMT2A 2122/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.