Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 5/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25760298 | 0.94 | MAPT (0.46) | KDM4ESMN1; SMN2ALDH1A1MAPTHTT | |
| SCHEMBL25760294 | 0.92 | RAB9A (0.40) | KDM4ESMN1; SMN2ALDH1A1MAPTHTT | |
| SCHEMBL4547065 | 0.92 | ALDH1A1 (0.45) | KDM4ESMN1; SMN2ALDH1A1HTTNPSR1 | |
| SCHEMBL21751461 | 0.90 | KDM4E (0.41) | KDM4ESMN1; SMN2ALDH1A1MAPTHTT | |
| SCHEMBL13484442 | 0.90 | ALDH1A1 (0.42) | KDM4ESMN1; SMN2ALDH1A1MAPTHTT | |
| SCHEMBL12735455 | 0.90 | ALDH1A1 (0.43) | KDM4ESMN1; SMN2ALDH1A1MAPTHTT | |
| SCHEMBL25760275 | 0.89 | THRB (0.36) | KDM4ESMN1; SMN2ALDH1A1MAPTHTT | |
| SCHEMBL25760289 | 0.89 | KMT2A (0.36) | SMN1; SMN2ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL10012889 | 0.89 | KDM4E (0.43) | KDM4ESMN1; SMN2ALDH1A1MAPTHTT | |
| SCHEMBL25760166 | 0.88 | THRB (0.38) | SMN1; SMN2ALDH1A1MAPTHTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11691976-B2 | Coelenterazine analogues | PROMEGA CORPORATION (US) | 2023-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11691976-B2 | Coelenterazine analogues | GLB1, SI, TCF7L2 | KDM4E 3302/4885SMN1; SMN2 3970/4885ALDH1A1 3541/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.