SCHEMBL25760435

SCHEMBL25760435

Cc1cccc(-c2cn3c(=O)c(Cc4ccc(C(F)(F)F)o4)nc-3c(Cc3ccccc3)[nH]2)c1F

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ ALKBH3 Q96Q83 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21751334 0.90 GNRHR (0.32) —
SCHEMBL21751307 0.90 LTB4R (0.31) —
SCHEMBL21751459 0.88 MEN1 (0.33) —
SCHEMBL21751332 0.87 — —
SCHEMBL19206642 0.85 KDM4E (0.32) ALKBH3
SCHEMBL25760462 0.85 ALPL (0.36) ALKBH3
SCHEMBL25760333 0.85 ADORA2B (0.37) —
SCHEMBL25760261 0.85 THRB (0.34) ALKBH3
SCHEMBL27213468 0.83 ALPL (0.33) —
SCHEMBL25760181 0.82 LTB4R (0.32) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11691976-B2 Coelenterazine analogues PROMEGA CORPORATION (US) 2023-07-04 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11691976-B2 Coelenterazine analogues GLB1, SI, TCF7L2 ALKBH3 3142/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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