Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.64 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.64 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.61 |
| ▸ | RORB | Q92753 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.50 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | GBA1 | P04062 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL178218 | 0.94 | ADORA3 (0.60) | ADORA3ADORA1ADORA2ALMNANPSR1 | |
| SCHEMBL257438 | 0.93 | ADORA3 (0.54) | ADORA3ADORA1ADORA2ALMNANPSR1 | |
| SCHEMBL165773 | 0.90 | ADORA3 (0.61) | ADORA3ADORA1ADORA2ALMNANPSR1 | |
| SCHEMBL10092885 | 0.88 | RORB (0.70) | ADORA3ADORA1ADORA2ALMNANPSR1 | |
| SCHEMBL10092883 | 0.85 | RORB (0.67) | ADORA3ADORA1ADORA2ARORBALDH1A1 | |
| SCHEMBL257432 | 0.85 | RORB (0.74) | ADORA3ADORA1ADORA2ALMNANPSR1 | |
| SCHEMBL27653923 | 0.85 | ALDH1A1 (0.64) | ADORA3NPSR1RORBALDH1A1HSD17B10 | |
| SCHEMBL257613 | 0.84 | RORB (0.52) | ADORA3ADORA1ADORA2ALMNANPSR1 | |
| SCHEMBL257393 | 0.83 | RORB (0.60) | ADORA3ADORA1ADORA2ALMNANPSR1 | |
| SCHEMBL257437 | 0.81 | RORB (0.76) | RORBALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012027965-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2012-03-08 | — | — | WO | disclosed |