Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 1/20 | 0.45 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.44 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.42 |
| ▸ | CHRNA2 | Q15822 | 2/20 | 0.42 |
| ▸ | CHRNA1 | P02708 | 2/20 | 0.42 |
| ▸ | CHRNB1 | P11230 | 2/20 | 0.42 |
| ▸ | CHRNB3 | Q05901 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.42 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | HTR3B | O95264 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25751700 | 0.88 | CYP11B2 (0.49) | CYP11B2PRMT5WDR77HSD11B1CHRNA7 | |
| SCHEMBL25767313 | 0.79 | CYP11B2 (0.49) | CYP11B2PRMT5WDR77HSD11B1CHRNA7 | |
| SCHEMBL16144645 | 0.77 | HSD11B1 (0.50) | CYP11B2PRMT5WDR77HSD11B1CHRNA7 | |
| SCHEMBL17774405 | 0.77 | CYP11B2 (0.53) | CYP11B2PRMT5WDR77HSD11B1CHRNA7 | |
| SCHEMBL17518824 | 0.75 | CYP11B2 (0.54) | CYP11B2PRMT5WDR77HSD11B1CHRNA7 | |
| SCHEMBL24059287 | 0.75 | CYP11B2 (0.57) | CYP11B2PRMT5WDR77HSD11B1CHRNA7 | |
| SCHEMBL17779065 | 0.75 | CYP11B2 (0.57) | CYP11B2CHRNA7CHRNB2CHRNA4ALDH1A1 | |
| SCHEMBL31339129 | 0.74 | GPR119 (0.56) | CYP11B2PRMT5WDR77HSD11B1CHRNA7 | |
| SCHEMBL25274630 | 0.74 | GPR119 (0.56) | CYP11B2PRMT5WDR77HSD11B1CHRNA7 | |
| SCHEMBL13841172 | 0.74 | CYP11B2 (0.55) | CYP11B2HSD11B1CHRNA7CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230203087-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230203087-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | RNGTT, NSUN2, ALKBH1 | CYP11B2 4377/4885PRMT5 983/4885WDR77 1337/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.