SCHEMBL25779341

SCHEMBL25779341

CCOC(C)CCOCCOS(C)(=O)=O

nearest known ligand 0.39

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.39
USP2 O75604 1/20 0.39
ALDH1A1 P00352 1/20 0.39
LMNA P02545 1/20 0.39
MMP9 P14780 1/20 0.39
ALOX15 P16050 1/20 0.39
TSHR P16473 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25779352 0.92 KDM4E (0.44) KDM4EUSP2ALDH1A1LMNAMMP9
SCHEMBL25779334 0.92 KDM4E (0.48) KDM4EUSP2ALDH1A1LMNAMMP9
SCHEMBL26465758 0.88 KDM4E (0.44) KDM4EUSP2ALDH1A1LMNAMMP9
SCHEMBL25779307 0.84 LMNA (0.40) KDM4EUSP2ALDH1A1LMNAMMP9
SCHEMBL28433372 0.80 LMNA (0.43) LMNA
SCHEMBL13369382 0.79 ALDH1A1 (0.46) KDM4EUSP2ALDH1A1LMNAMMP9
SCHEMBL24089553 0.76 KDM4E (0.40) KDM4EUSP2ALDH1A1LMNAMMP9
SCHEMBL17022252 0.76 TSHR (0.52) KDM4EUSP2ALDH1A1LMNAMMP9
SCHEMBL5174514 0.76 TSHR (0.52) KDM4EUSP2ALDH1A1LMNAMMP9
SCHEMBL23833996 0.76 TSHR (0.52) KDM4EUSP2ALDH1A1LMNAMMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230212103-A1 POLYETHYLENE GLYCOL DERIVATIVE AND USE THEREOF HANMI PHARM. CO., LTD. (KR) 2023-07-06 US disclosed
US-20230139745-A1 NON-PEPTIDIC POLYMERIC LINKER COMPOUND, CONJUGATE COMPRISING SAME LINKER COMPOUND, AND METHODS FOR PREPARING SAME LINKER COMPOUND AND CONJUGATE HANMI PHARM. CO., LTD. (KR) 2023-05-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230139745-A1 NON-PEPTIDIC POLYMERIC LINKER COMPOUND, CONJUGATE COMPRISING SAME LINKER COMPOUND, AND METHODS FOR PREPARING SAME LINKER COMPOUND AND CONJUGATE FCGR1A, FCGR3B, FCGR2A KDM4E 3512/4885USP2 1841/4885ALDH1A1 4031/4885
US-20230212103-A1 POLYETHYLENE GLYCOL DERIVATIVE AND USE THEREOF RPN2, MPDU1, RPN1 KDM4E 3528/4885USP2 1181/4885ALDH1A1 332/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.