Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | ACP1 | P24666 | 2/20 | 0.51 |
| ▸ | NNMT | P40261 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | TACR1 | P25103 | 1/20 | 0.47 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.46 |
| ▸ | RHOC | P08134 | 3/20 | 0.46 |
| ▸ | RHOA | P61586 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.44 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL263685 | 0.89 | LMNA (0.65) | LMNAACP1NNMTALDH1A1TACR1 | |
| SCHEMBL15542485 | 0.85 | LMNA (0.55) | LMNAACP1ALDH1A1TACR1GPR35 | |
| SCHEMBL20568446 | 0.84 | ALDH1A1 (0.54) | LMNAACP1ALDH1A1TACR1GPR35 | |
| SCHEMBL4013181 | 0.83 | LMNA (0.54) | LMNAACP1NNMTALDH1A1TACR1 | |
| SCHEMBL22387603 | 0.81 | MAPT (0.53) | LMNAACP1NNMTALDH1A1TACR1 | |
| SCHEMBL20568430 | 0.81 | LMNA (0.49) | LMNAACP1ALDH1A1TACR1GPR35 | |
| SCHEMBL15542219 | 0.81 | SMN1; SMN2 (0.64) | LMNAACP1ALDH1A1TACR1RHOC | |
| SCHEMBL12475154 | 0.80 | GPR35 (0.56) | LMNAACP1ALDH1A1TACR1GPR35 | |
| SCHEMBL18763045 | 0.80 | NNMT (0.57) | LMNAACP1NNMTALDH1A1TACR1 | |
| SCHEMBL16904552 | 0.79 | MAPT (0.53) | LMNAACP1ALDH1A1GPR35MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125751-A1 | DIA-BASED QUANTITATIVE CHEMICAL PROTEOMICS TARGET SCREENING METHOD | 北京大学 | 2023-07-06 | — | — | WO | disclosed |