SCHEMBL2580669

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2580505	0.98	FAAH (0.41)	FAAHSELPCNR1ALDH1A1HPGD
	SCHEMBL16312532	0.89	PTPN1 (0.43)	FAAHCNR1PTPN1HDAC3HDAC4
	SCHEMBL2582843	0.85	DNM1 (0.45)	FAAHSELPCNR1HDAC3HDAC4
	SCHEMBL12063395	0.85	HDAC3 (0.38)	FAAHALDH1A1HPGDPTPN1HDAC3
	SCHEMBL2575373	0.85	FAAH (0.42)	FAAHCNR1PTPN1CNR2HDAC3
	SCHEMBL9843227	0.85	HDAC3 (0.38)	FAAHALDH1A1PTPN1HDAC3HDAC4
	SCHEMBL15195617	0.85	DNM1 (0.40)	FAAHSELPCNR1PTPN1HDAC3
	SCHEMBL12244714	0.85	GLP1R (0.35)	FAAHCNR1PTPN1CNR2HDAC3
	SCHEMBL23395460	0.84	LMNA (0.48)	FAAHCNR1ALDH1A1HPGDMAPT
	SCHEMBL20883500	0.84	DNM1 (0.50)	FAAHCNR1MEN1KMT2ADNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.