SCHEMBL2582843

SCHEMBL2582843

CCCNC(=O)CCCCC(S)CCS

nearest known ligand 0.45

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 2/20 0.45
FAAH O00519 7/20 0.44
CNR1 P21554 2/20 0.42
CASP2 P42575 1/20 0.40
HDAC3 O15379 2/20 0.38
HDAC4 P56524 2/20 0.38
HDAC1 Q13547 2/20 0.38
HDAC7 Q8WUI4 2/20 0.38
HDAC2 Q92769 2/20 0.38
HDAC10 Q969S8 2/20 0.38
HDAC11 Q96DB2 2/20 0.38
HDAC8 Q9BY41 2/20 0.38
HDAC6 Q9UBN7 2/20 0.38
HDAC9 Q9UKV0 2/20 0.38
HDAC5 Q9UQL6 2/20 0.38
NAAA Q02083 1/20 0.38
LPAR2 Q9HBW0 1/20 0.37
EPHX2 P34913 2/20 0.37
SELP P16109 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20883500 0.92 DNM1 (0.50) DNM1FAAHCNR1CASP2NAAA
SCHEMBL9316073 0.89 CASP2 (0.56) DNM1FAAHCASP2NAAAEPHX2
SCHEMBL24093714 0.87 FAAH (0.52) DNM1FAAHEPHX2
SCHEMBL23395460 0.86 LMNA (0.48) DNM1FAAHCNR1HDAC3HDAC4
SCHEMBL2580669 0.85 FAAH (0.42) DNM1FAAHCNR1HDAC3HDAC4
SCHEMBL16864736 0.84 ADRA1A (0.41) DNM1FAAHHDAC3HDAC4HDAC1
SCHEMBL2580505 0.84 FAAH (0.41) DNM1FAAHCNR1HDAC3HDAC4
SCHEMBL9843227 0.84 HDAC3 (0.38) DNM1FAAHHDAC3HDAC4HDAC1
SCHEMBL12063395 0.84 HDAC3 (0.38) DNM1FAAHHDAC3HDAC4HDAC1
SCHEMBL2575373 0.84 FAAH (0.42) FAAHCNR1HDAC3HDAC4HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060122100-A1 Melanin extinguisher OGA RESEARCH, INCORPORATED (JP) 2006-06-08 US claimed
EP-1547590-A1 MELANIN EXTINGUISHER Oga Research, Incorporated (JP) 2005-06-29 EP claimed
US-20230279186-A1 Hydrogels Based On Functionalized Polysaccharides ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) 2023-09-07 US disclosed
US-11542371-B2 Hydrogels based on functionalized polysaccharides ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) 2023-01-03 US disclosed
US-20200270402-A1 Hydrogels Based On Functionalized Polysaccharides ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) 2020-08-27 US disclosed
US-20170168042-A1 CONTROLLING THE ARCHITECTURE, COORDINATION, AND REACTIVITY OF NANOPARTICLE COATING UTILIZING AN AMINO ACID CENTRAL SCAFFOLD The Florida State University Research Foundation, Inc. 2017-06-15 US disclosed
EP-2634135-B1 SYNTHESIS OF MOLECULAR SIEVES FOR MODIFYING THE SURFACES OF NANOPARTICLES HAVING AMPHOTERIC IONS, AND APPLICATION THEREOF POSTECH ACAD IND FOUND (KR) 2016-04-27 EP disclosed
US-20150111303-A1 SYNTHESIS OF MOLECULE ON NANOPARTICLE SURFACE FOR STABLE DETECTION OF NITROAROMATIC EXPLOSIVES, AND SENSOR USING SAME POSTECH ACAD IND FOUND (KR) 2015-04-23 US disclosed
US-8048911-B2 Melanin eliminator preparation OGA Research, Inc. (JP) 2011-11-01 US disclosed
US-20090093541-A1 MELANIN ELIMINATOR PREPARATION OGA RESEARCH, INC (JP) 2009-04-09 US disclosed
US-20060122100-A1 Melanin extinguisher OGA RESEARCH, INCORPORATED (JP) 2006-06-08 US disclosed
EP-1547590-A1 MELANIN EXTINGUISHER Oga Research, Incorporated (JP) 2005-06-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200270402-A1 Hydrogels Based On Functionalized Polysaccharides CD44, ALG1, CSGALNACT1 DNM1 4336/4885FAAH 2346/4885CNR1 3907/4885
US-20060122100-A1 Melanin extinguisher TYR, MC1R, MITF DNM1 1426/4885FAAH 4202/4885CNR1 3876/4885
US-20170168042-A1 CONTROLLING THE ARCHITECTURE, COORDINATION, AND REACTIVITY OF NANOPARTICLE COATING UTILIZING AN AMINO ACID CENTRAL SCAFFOLD CLTA, ALAD, PELP1 DNM1 1908/4885FAAH 4276/4885CNR1 4676/4885
US-11542371-B2 Hydrogels based on functionalized polysaccharides CD44, ALG1, CSGALNACT1 DNM1 4336/4885FAAH 2346/4885CNR1 3907/4885
US-20090093541-A1 MELANIN ELIMINATOR PREPARATION TYR, MC1R, MCHR1 DNM1 1048/4885FAAH 3678/4885CNR1 3608/4885
US-20230279186-A1 Hydrogels Based On Functionalized Polysaccharides CD44, ALG1, CSGALNACT1 DNM1 4336/4885FAAH 2346/4885CNR1 3907/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.