SCHEMBL25495665

SCHEMBL25495665

CCCc1cn(CCOCCOCCOCCNC(=O)CCOCCOCCC(=O)Oc2c(F)c(F)c(F)c(F)c2F)nn1

nearest known ligand 0.37

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 8/20 0.37
LGALS3 P17931 2/20 0.35
F2RL1 P55085 1/20 0.35
FOLH1 Q04609 4/20 0.35
DRD4 P21917 2/20 0.35
DRD3 P35462 2/20 0.35
OPRM1 P35372 2/20 0.35
OPRD1 P41143 1/20 0.34
OPRK1 P41145 1/20 0.34
PLK1 P53350 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22083577 0.83 DRD2 (0.44) DRD2LGALS3FOLH1OPRM1
SCHEMBL25495603 0.83 DGAT1 (0.36) F2RL1OPRM1
SCHEMBL25900322 0.81 LGALS3 (0.39) LGALS3F2RL1FOLH1OPRM1PLK1
SCHEMBL25982998 0.81 LGALS3 (0.38) DRD2LGALS3F2RL1DRD4DRD3
SCHEMBL25979356 0.81 LGALS3 (0.35) DRD2LGALS3F2RL1DRD4DRD3
SCHEMBL25835937 0.81 DRD2 (0.42) DRD2LGALS3FOLH1OPRM1
SCHEMBL25495188 0.80 LGALS3 (0.50) LGALS3OPRM1
SCHEMBL25523201 0.80 LGALS3 (0.44) LGALS3F2RL1OPRM1
SCHEMBL17480080 0.78 CA12 (0.34)
SCHEMBL24894530 0.78 EPHX2 (0.47) DRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230158155-A1 Cell Surface Receptor Binding Compounds and Conjugates LYCIA THERAPEUTICS, INC. 2023-05-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230158155-A1 Cell Surface Receptor Binding Compounds and Conjugates M6PR, ASGR1, IGF2R DRD2 1929/4885LGALS3 293/4885F2RL1 328/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.