Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | POU2F2 | P09086 | 3/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29068639 | 0.82 | ALDH1A1 (0.51) | ALDH1A1ROCK2ROCK1P2RX7RIPK1 | |
| SCHEMBL5315965 | 0.80 | SETDB1 (0.43) | ALDH1A1NPSR1KMT2AEPHX2CYP1A2 | |
| SCHEMBL14232838 | 0.80 | NPSR1 (0.53) | NPSR1ROCK2ROCK1P2RX7KMT2A | |
| SCHEMBL29788838 | 0.79 | RIPK1 (0.46) | ROCK2ROCK1RIPK1 | |
| SCHEMBL885252 | 0.78 | KMT2A (0.48) | ALDH1A1NPSR1RIPK1KMT2A | |
| SCHEMBL29145665 | 0.77 | ALDH1A1 (0.44) | ALDH1A1ROCK2ROCK1P2RX7RIPK1 | |
| SCHEMBL5315312 | 0.76 | P2RX7 (0.52) | P2RX7RIPK1KMT2AEPHX2 | |
| SCHEMBL29788849 | 0.74 | NPSR1 (0.43) | ALDH1A1NPSR1ROCK2ROCK1P2RX7 | |
| SCHEMBL27470038 | 0.74 | RIPK1 (0.42) | ALDH1A1ROCK2ROCK1P2RX7RIPK1 | |
| SCHEMBL28171338 | 0.74 | ALDH1A1 (0.43) | ALDH1A1ROCK2ROCK1P2RX7RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122036718-A | ALK5 inhibitor and preparation method and application thereof | 安炎达医药技术(广州)有限公司 | 2026-05-15 | — | — | CN | disclosed |
| US-11845767-B2 | Arginase inhibitors | RIJKSUNIVERSITEIT GRONINGEN (NL) | 2023-12-19 | — | — | US | disclosed |
| WO-2023125825-A1 | ANTICORONVIRAL COMPOUNDS AND COMPOSITIONS AND USES THEREOF | SHANGHAI CUREGENE PHARMACEUTICAL CO., LTD. (CN) | 2023-07-06 | — | — | WO | disclosed |
| US-20220227791-A1 | NOVEL ARGINASE INHIBITORS | RIJKSUNIVERSITEIT GRONINGEN (NL) | 2022-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220227791-A1 | NOVEL ARGINASE INHIBITORS | ARG1, ARG2, ARGLU1 | ALDH1A1 764/4885NPSR1 596/4885ROCK2 437/4885 |
| US-11845767-B2 | Arginase inhibitors | ARG1, ARG2, ARGLU1 | ALDH1A1 747/4885NPSR1 606/4885ROCK2 399/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.