SCHEMBL2584081

SCHEMBL2584081

C[Si](C)(C)O[SiH](CCCCc1ccccc1)O[Si](C)(C)C

nearest known ligand 0.44

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 12/20 0.44
L3MBTL1 Q9Y468 1/20 0.43
MAOA P21397 1/20 0.42
MAOB P27338 2/20 0.41
IDO1 P14902 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL704369 0.79 L3MBTL1 (0.47) SIGMAR1L3MBTL1MAOAMAOBIDO1
SCHEMBL28660287 0.79 TDP1 (0.35) SIGMAR1
SCHEMBL6325312 0.78 SIGMAR1 (0.48) SIGMAR1L3MBTL1MAOAMAOB
SCHEMBL19470822 0.78 SIGMAR1 (0.48) SIGMAR1L3MBTL1MAOAMAOB
SCHEMBL3110910 0.78 SIGMAR1 (0.48) SIGMAR1L3MBTL1MAOAMAOB
SCHEMBL19470840 0.78 SIGMAR1 (0.48) SIGMAR1L3MBTL1MAOAMAOB
SCHEMBL19470846 0.78 SIGMAR1 (0.48) SIGMAR1L3MBTL1MAOAMAOB
SCHEMBL19470849 0.78 SIGMAR1 (0.48) SIGMAR1L3MBTL1MAOAMAOB
SCHEMBL2577645 0.77 KCNA3 (0.55)
SCHEMBL703456 0.76 L3MBTL1 (0.44) SIGMAR1L3MBTL1MAOAMAOBIDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8049024-B2 Heterogenized rhodium complexes, methods of their synthesis and application as hydrosilylation catalysts ADAM MICKIEWICZ UNIVERSITY (PL) 2011-11-01 US disclosed
US-20100048932-A1 New Heterogenized Rhodium Complexes, Methods of their Synthesis and Application as Hydrosilylation Catalysts ADAM MICKIEWICZ UNIVERSITY (PL) 2010-02-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100048932-A1 New Heterogenized Rhodium Complexes, Methods of their Synthesis and Application as Hydrosilylation Catalysts SQLE, HAO2, IPO11 SIGMAR1 70/4885L3MBTL1 4346/4885MAOA 2749/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.