Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.42 |
| ▸ | HTR3B | O95264 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.42 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2579648 | 0.91 | HTR3E (0.48) | POLBNPSR1L3MBTL1TP53SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL2579274 | 0.87 | GAA (0.46) | POLBNPSR1L3MBTL1TP53SMN1; SMN2 | |
| SCHEMBL16789887 | 0.75 | HTR3E (0.52) | POLBL3MBTL1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL4081119 | 0.75 | POLB (0.68) | POLBL3MBTL1SMN1; SMN2TAAR1ALDH1A1 | |
| SCHEMBL4631544 | 0.75 | POLB (0.68) | POLBL3MBTL1SMN1; SMN2TAAR1ALDH1A1 | |
| Trifluoromethanesulfonic Acid SCHEMBL2584928 | 0.74 | NOX4 (0.50) | SMN1; SMN2LMNA | |
| SCHEMBL11178945 | 0.72 | SIGMAR1 (0.54) | POLBL3MBTL1ALDH1A1MAPTKMT2A | |
| SCHEMBL15328020 | 0.71 | HDAC1 (0.48) | POLBL3MBTL1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL16786533 | 0.69 | ACHE (0.58) | POLBSMN1; SMN2ALDH1A1HPGDMAPT | |
| SCHEMBL26186618 | 0.69 | POLB (0.69) | POLBL3MBTL1SMN1; SMN2TAAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8722897-B2 | Metal complexes of thiourea and derivatives as metal delivering anti-cancer and anti-inflammatory agents | GOLDPORP PHARMA LIMITED (CN) | 2014-05-13 | — | — | US | disclosed |
| WO-2011134275-A1 | METAL COMPLEXES OF THIOUREA AND THEIR DERIVATIVES AS METAL DELIVERING ANTI-CANCER AND ANTI-INFLAMMATORY AGENTS | CHE CHI-MING (CN) | 2011-11-03 | — | — | WO | disclosed |
| US-20110269730-A1 | Metal Complexes of Thiourea and Derivatives as Metal Delivering Anti-Cancer and Anti-Inflammatory Agents | GOLDPORP PHARMA LIMITED (CN) | 2011-11-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110269730-A1 | Metal Complexes of Thiourea and Derivatives as Metal Delivering Anti-Cancer and Anti-Inflammatory Agents | CLIC1, SLC30A5, TIA1 | POLB 2379/4885NPSR1 3711/4885L3MBTL1 307/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.