SCHEMBL25848203

SCHEMBL25848203

C=C(C)C(=O)OCC(C)(C)CSc1ccc2cc(-c3ccc(CCCCC)cc3OC(F)(F)F)c(=O)oc2c1

nearest known ligand 0.32

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
STS P08842 1/20 0.32
GPR55 Q9Y2T6 3/20 0.32
TRPV1 Q8NER1 1/20 0.31
TERT O14746 1/20 0.30
CNR1 P21554 2/20 0.30
CNR2 P34972 2/20 0.30
GPR18 Q14330 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22625132 0.93 GPR55 (0.31) GPR55
SCHEMBL22625096 0.90 TRPV1 (0.31) GPR55TRPV1
SCHEMBL25848202 0.89 TP53 (0.32) GPR55CNR1CNR2
SCHEMBL25848187 0.87 MAOB (0.37) STS
SCHEMBL25848173 0.86 FPR1 (0.30) STS
SCHEMBL22624914 0.86 STS (0.30) STS
SCHEMBL22624989 0.86 TERT (0.31) TERT
SCHEMBL25848233 0.86 PPARD (0.31)
SCHEMBL22625332 0.85 TERT (0.30) TERT
SCHEMBL21735045 0.85 ALOX5 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11702396-B2 Hydrophobic compounds for optically active devices Johnson & Johnson Surgical Vision, Inc. (US) 2023-07-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11702396-B2 Hydrophobic compounds for optically active devices UACA, CRYZ, TRPA1 STS 4081/4885GPR55 650/4885TRPV1 19/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.