Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.30 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2584542 | 0.83 | CES2 (0.33) | GAACTSSCTSK | |
| SCHEMBL4325043 | 0.82 | MEN1 (0.31) | MEN1NPC1GAARAB9AKMT2A | |
| SCHEMBL2578534 | 0.82 | ACKR3 (0.40) | CTSSCTSK | |
| SCHEMBL2588069 | 0.80 | AAK1 (0.34) | CTSSCTSK | |
| SCHEMBL2587766 | 0.80 | CTSS (0.35) | MEN1GAAKMT2ACTSSCTSK | |
| SCHEMBL2585429 | 0.77 | CTSS (0.33) | CTSSCTSK | |
| SCHEMBL2581151 | 0.76 | CHRNA1 (0.36) | MEN1NPC1GAARAB9AKMT2A | |
| SCHEMBL4517781 | 0.76 | PPARA (0.46) | CTSSCTSK | |
| SCHEMBL4517788 | 0.76 | PPARA (0.46) | CTSSCTSK | |
| SCHEMBL2584672 | 0.76 | AAK1 (0.34) | RAB9ACTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8048878-B2 | Two cyclic cinnamide compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2011-11-01 | — | — | US | disclosed |