Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 3/20 | 0.31 |
| ▸ | CTSK | P43235 | 3/20 | 0.31 |
| ▸ | ACE | P12821 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2587766 | 0.88 | CTSS (0.35) | AAK1CTSSCTSKACE | |
| SCHEMBL2578534 | 0.88 | ACKR3 (0.40) | AAK1CTSSCTSK | |
| SCHEMBL2581151 | 0.84 | CHRNA1 (0.36) | AAK1 | |
| SCHEMBL2584542 | 0.84 | CES2 (0.33) | AAK1CTSSCTSK | |
| SCHEMBL2584672 | 0.84 | AAK1 (0.34) | AAK1CTSSCTSKACE | |
| SCHEMBL2588125 | 0.84 | AAK1 (0.36) | AAK1CTSSCTSKACE | |
| SCHEMBL2585429 | 0.82 | CTSS (0.33) | AAK1CTSSCTSKACE | |
| SCHEMBL2586648 | 0.80 | MEN1 (0.31) | CTSSCTSK | |
| SCHEMBL2587439 | 0.79 | CTSS (0.41) | CTSSCTSK | |
| SCHEMBL2463123 | 0.76 | CTSK (0.35) | CTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8048878-B2 | Two cyclic cinnamide compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2011-11-01 | — | — | US | disclosed |