Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 3/20 | 0.33 |
| ▸ | CTSK | P43235 | 2/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 4/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ACE | P12821 | 1/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.30 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.30 |
| ▸ | AKT1 | P31749 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2584672 | 0.89 | AAK1 (0.34) | CTSSCTSKAAK1ACE | |
| SCHEMBL2587439 | 0.89 | CTSS (0.41) | CTSSCTSKLMNA | |
| SCHEMBL2588125 | 0.87 | AAK1 (0.36) | CTSSCTSKAAK1ACE | |
| SCHEMBL2581151 | 0.85 | CHRNA1 (0.36) | AAK1SLC6A3GABRB1GABRB2 | |
| SCHEMBL2588069 | 0.82 | AAK1 (0.34) | CTSSCTSKAAK1ACE | |
| SCHEMBL2578534 | 0.82 | ACKR3 (0.40) | CTSSCTSKAAK1 | |
| SCHEMBL2587766 | 0.82 | CTSS (0.35) | CTSSCTSKAAK1ACE | |
| SCHEMBL2575528 | 0.81 | ALDH1A1 (0.47) | LMNA | |
| SCHEMBL2583802 | 0.80 | ERCC5 (0.42) | SLC6A3LMNA | |
| SCHEMBL2584542 | 0.78 | CES2 (0.33) | CTSSCTSKAAK1AKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8048878-B2 | Two cyclic cinnamide compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2011-11-01 | — | — | US | disclosed |