Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 12/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 12/20 | 0.39 |
| ▸ | YAP1 | P46937 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25876578 | 0.85 | ITGB3 (0.39) | ITGB3ITGA2BEPHX2 | |
| SCHEMBL12308621 | 0.79 | CHRM2 (0.43) | ITGB3ITGA2B | |
| SCHEMBL25870573 | 0.77 | PTPN1 (0.45) | ITGB3ITGA2BEPHX2MEN1KMT2A | |
| SCHEMBL5889076 | 0.77 | YAP1 (0.56) | YAP1 | |
| SCHEMBL12308617 | 0.76 | RIPK1 (0.36) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL25870422 | 0.76 | EPHX2 (0.48) | ITGB3ITGA2BYAP1EPHX2MEN1 | |
| SCHEMBL12308371 | 0.75 | GNAI3 (0.40) | ITGB3ITGA2B | |
| SCHEMBL8375991 | 0.75 | KEAP1 (0.44) | KMT2A | |
| SCHEMBL12308615 | 0.74 | MEN1 (0.38) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL12308632 | 0.74 | LMNA (0.49) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023116920-A1 | PENTA- FUSED HEXA-HETEROCYCLIC COMPOUND, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE | 杭州多域生物技术有限公司 | 2023-06-29 | — | — | WO | disclosed |