Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACVR1 | Q04771 | 6/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CAMKK1 | Q8N5S9 | 1/20 | 0.43 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.43 |
| ▸ | SDCBP | O00560 | 2/20 | 0.43 |
| ▸ | SDC2 | P34741 | 2/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.39 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25920054 | 0.91 | NPC1 (0.45) | ACVR1MAPTSMN1; SMN2CREBBPCAMKK1 | |
| SCHEMBL25331038 | 0.84 | MAPK1 (0.42) | ACVR1CREBBPSDCBPSDC2MAPK1 | |
| SCHEMBL30477291 | 0.84 | MAPK1 (0.42) | ACVR1CREBBPSDCBPSDC2MAPK1 | |
| SCHEMBL25918414 | 0.83 | ALOX15 (0.50) | ALOX15MAPTSMN1; SMN2KDM4ESDCBP | |
| SCHEMBL25920061 | 0.82 | MAPK1 (0.40) | CREBBPSDCBPSDC2MAPK1EGFR | |
| SCHEMBL25918382 | 0.81 | SDCBP (0.55) | ALOX15MAPTSMN1; SMN2KDM4ESDCBP | |
| SCHEMBL25920004 | 0.81 | MET (0.49) | ALOX15MAPTSMN1; SMN2KDM4ESDCBP | |
| SCHEMBL25919934 | 0.80 | CYP11B1 (0.49) | ALOX15MAPTSMN1; SMN2CREBBPKDM4E | |
| SCHEMBL25920245 | 0.79 | ALOX15 (0.43) | ALOX15MAPTSMN1; SMN2KDM4ESDCBP | |
| SCHEMBL25919570 | 0.79 | ALOX15 (0.45) | ALOX15MAPTSMN1; SMN2KDM4ESDCBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023132606-A1 | NOVEL ISOINDOLINONE DERIVATIVE COMPOUNDS AS CASPASE INHIBITORS | 주식회사 이노보테라퓨틱스 | 2023-07-13 | — | — | WO | disclosed |