Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.44 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.43 |
| ▸ | SDCBP | O00560 | 1/20 | 0.43 |
| ▸ | SDC2 | P34741 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 2/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25920003 | 0.90 | MET (0.47) | METADAM17SDCBPSDC2MCL1 | |
| SCHEMBL30477317 | 0.83 | MET (0.42) | METADAM17SDCBPSDC2EGFR | |
| SCHEMBL25332196 | 0.83 | MET (0.42) | METADAM17SDCBPSDC2EGFR | |
| SCHEMBL25918382 | 0.82 | SDCBP (0.55) | SDCBPSDC2ALOX15SMN1; SMN2MAPT | |
| SCHEMBL25918495 | 0.82 | MAP3K5 (0.47) | SDCBPSDC2ALOX15SMN1; SMN2MAPT | |
| SCHEMBL25920008 | 0.82 | SDCBP (0.40) | METAKR1C3AKR1C2ADAM17SDCBP | |
| SCHEMBL25920056 | 0.81 | ACVR1 (0.44) | SDCBPSDC2ALOX15SMN1; SMN2MAPT | |
| SCHEMBL25920245 | 0.78 | ALOX15 (0.43) | SDCBPSDC2ALOX15SMN1; SMN2MAPT | |
| SCHEMBL25918414 | 0.78 | ALOX15 (0.50) | SDCBPSDC2MCL1ALOX15SMN1; SMN2 | |
| SCHEMBL25920286 | 0.77 | NTSR1 (0.45) | SDCBPSDC2ALOX15SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023132606-A1 | NOVEL ISOINDOLINONE DERIVATIVE COMPOUNDS AS CASPASE INHIBITORS | 주식회사 이노보테라퓨틱스 | 2023-07-13 | — | — | WO | disclosed |