Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 5/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25923906 | 0.78 | KDM1A (0.46) | SMN1; SMN2KDM1AKMT2AALDH1A1 | |
| SCHEMBL25923900 | 0.76 | — | — | |
| SCHEMBL25923937 | 0.75 | KDM1A (0.40) | KDM1ACYP2D6 | |
| SCHEMBL25923931 | 0.71 | HTR4 (0.33) | KDM1ACYP2D6 | |
| SCHEMBL21088586 | 0.70 | KDM1A (0.31) | KDM1A | |
| SCHEMBL21088883 | 0.70 | KDM1A (0.44) | HTTSMN1; SMN2KDM1A | |
| SCHEMBL21088867 | 0.70 | HTR4 (0.35) | KDM1A | |
| SCHEMBL25924012 | 0.69 | L3MBTL1 (0.45) | MAPTHTTSMN1; SMN2KDM1AMEN1 | |
| SCHEMBL25923925 | 0.68 | KDM1A (0.42) | KDM1ACYP2D6 | |
| SCHEMBL25924008 | 0.68 | KDM1A (0.32) | KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3532459-B1 | LSD1 INHIBITORS AND MEDICAL USES THEREOF | CONSTELLATION PHARMACEUTICALS INC (US) | 2023-08-02 | — | — | EP | disclosed |