Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.40 |
| ▸ | STS | P08842 | 1/20 | 0.39 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.39 |
| ▸ | ABAT | P80404 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8620440 | 0.83 | KMT2A (0.62) | ALDH1A1CYP2A6KMT2AALDH1A3KDM4E | |
| SCHEMBL8620443 | 0.83 | KMT2A (0.62) | ALDH1A1CYP2A6KMT2AALDH1A3KDM4E | |
| SCHEMBL24677898 | 0.83 | ALDH1A1 (0.47) | ALDH1A1CYP2A6KMT2AALDH1A3KDM4E | |
| SCHEMBL20634390 | 0.79 | LMNA (0.47) | ALDH1A1KMT2AKDM4EMAPTLMNA | |
| SCHEMBL12153541 | 0.77 | TDP1 (0.46) | ALDH1A1KMT2AKDM4EMAPTPARP10 | |
| SCHEMBL18461315 | 0.76 | CA4 (0.42) | ALDH1A1KMT2AMAPTTSHRSMN1; SMN2 | |
| SCHEMBL4643258 | 0.75 | KMT2A (0.56) | ALDH1A1CYP2A6KMT2AALDH1A3KDM4E | |
| SCHEMBL24464714 | 0.74 | LTA4H (0.50) | ALDH1A1KMT2AMAPTPARP10LMNA | |
| SCHEMBL24236789 | 0.74 | ESR1 (0.41) | ALDH1A1KDM4EMAPTLMNATP53 | |
| SCHEMBL15177135 | 0.74 | KMT2A (0.41) | ALDH1A1CYP2A6KMT2AALDH1A3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230227493-A1 | CARBOXY SUBSTITUTED GLUCOCORTICOID RECEPTOR AGONISTS | ELI LILLY AND COMPANY | 2023-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230227493-A1 | CARBOXY SUBSTITUTED GLUCOCORTICOID RECEPTOR AGONISTS | NR3C1, MC2R, NR3C2 | ALDH1A1 2971/4885CYP2A6 677/4885KMT2A 2407/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.