Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 8/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.42 |
| ▸ | CTSB | P07858 | 3/20 | 0.42 |
| ▸ | CTSS | P25774 | 3/20 | 0.41 |
| ▸ | CTSL | P07711 | 2/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | REN | P00797 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25976319 | 1.00 | OPRM1 (0.42) | OPRM1OPRD1OPRK1CTSBCTSS | |
| SCHEMBL25877902 | 0.84 | CHRNB2 (0.45) | CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL25877836 | 0.81 | QRFPR (0.36) | OPRM1OPRD1OPRK1CTSBCHRNB2 | |
| SCHEMBL24183741 | 0.81 | CHRNA1 (0.42) | OPRM1OPRD1OPRK1CTSBCTSS | |
| SCHEMBL26154352 | 0.81 | REN (0.45) | OPRM1OPRD1OPRK1CTSBCTSS | |
| SCHEMBL24183746 | 0.79 | OPRD1 (0.45) | OPRM1OPRD1OPRK1CTSBCTSS | |
| SCHEMBL25877088 | 0.79 | AKT1 (0.47) | OPRM1OPRD1OPRK1 | |
| SCHEMBL24999273 | 0.79 | CTSS (0.43) | OPRM1OPRD1OPRK1CTSBCTSS | |
| SCHEMBL27354682 | 0.79 | CTSB (0.48) | OPRM1OPRD1OPRK1CTSBCTSS | |
| SCHEMBL25757530 | 0.79 | CTSB (0.37) | OPRM1OPRD1OPRK1CTSBCHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4223318-A1 | ANTITUMOR COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Duality Biologics (Suzhou) Co., Ltd. (CN) | 2023-08-09 | — | — | EP | disclosed |