Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 5/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 5/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.31 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23486043 | 0.88 | ALDH1A1 (0.33) | MAPTKDM4EHPGDGAA | |
| SCHEMBL5460805 | 0.75 | TAS1R3 (0.38) | TAS1R3TAS1R1MAPTPOLBHPGD | |
| SCHEMBL14767358 | 0.71 | ALDH1A1 (0.39) | TAS1R3TAS1R1MAPTPOLBKDM4E | |
| SCHEMBL2139729 | 0.69 | LCK (0.50) | MAPTPOLBKDM4EHPGDTSHR | |
| SCHEMBL1753958 | 0.69 | HTT (0.52) | MAPTKDM4EHPGDTSHRHSD17B10 | |
| SCHEMBL25647564 | 0.68 | NNMT (0.51) | KDM4EHPGDTSHRGAA | |
| SCHEMBL11065578 | 0.68 | KDM4E (0.52) | MAPTPOLBKDM4EHPGDHSD17B10 | |
| SCHEMBL6927455 | 0.68 | TAAR1 (0.39) | TAS1R3TAS1R1MAPTPOLBKDM4E | |
| SCHEMBL10289261 | 0.67 | KDM4E (0.41) | MAPTPOLBKDM4EHPGDHSD17B10 | |
| SCHEMBL5460148 | 0.66 | KDM4E (0.41) | TAS1R3TAS1R1KDM4EHPGDSTING1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230255942-A1 | CRF1 RECEPTOR ANTAGONIST FOR THE TREATMENT OF CONGENITAL ADRENAL HYPERPLASIA | QUOTIENT SCIENCES LIMITED (GB) | 2023-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230255942-A1 | CRF1 RECEPTOR ANTAGONIST FOR THE TREATMENT OF CONGENITAL ADRENAL HYPERPLASIA | CRHR1, MC2R, CRHR2 | TAS1R3 1998/4885TAS1R1 1028/4885MAPT 4436/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.