SCHEMBL2600360

SCHEMBL2600360

CC(C)C(=S)NC(C)(C)C

nearest known ligand 0.50

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
EPHX1 P07099 1/20 0.37
POLB P06746 1/20 0.36
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22060199 0.78 MEN1 (0.46) MEN1KMT2AEPHX1POLB
SCHEMBL19035755 0.72 POLB (0.37) MEN1KMT2AEPHX1POLBHTT
SCHEMBL10211106 0.69
SCHEMBL1276388 0.67 MEN1 (1.00) MEN1KMT2AEPHX1POLBHTT
SCHEMBL2833590 0.67 MEN1 (0.60) MEN1KMT2AEPHX1POLBHTT
SCHEMBL19484935 0.65 MEN1 (0.43) MEN1KMT2AEPHX1POLBHTT
SCHEMBL19484938 0.65 MEN1 (0.43) MEN1KMT2AEPHX1POLB
SCHEMBL583850 0.65
SCHEMBL25922318 0.65
SCHEMBL2601892 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230226214-A1 BIFUNCTIONAL BRIDGING COMPOSITIONS FOR VIRAL TRANSDUCTION LYCIA THERAPEUTICS, INC. 2023-07-20 US disclosed
US-20230144211-A1 ANTIFOLATE LINKER-DRUGS AND ANTIBODY-DRUG CONJUGATES BYONDIS B.V. (NL) 2023-05-11 US disclosed
US-20220119392-A1 ANTIFOLATE LINKER-DRUGS AND ANTIBODY-DRUG CONJUGATES BYONDIS B.V. (NL) 2022-04-21 US disclosed
US-20200172575-A1 PEPTIDE COMPOUND AND APPLICATION THEREOF, AND COMPOSITION CONTAINING PEPTIDE COMPOUND XDCEXPLORER (SHANGHAI) CO., LTD. (CN) 2020-06-04 US disclosed
US-8980245-B2 PEG-interferon λ1 conjugates and methods of treating viral infections NANOGEN PHARMACEUTICAL BIOTECHNOLOGY (VN) 2015-03-17 US disclosed
US-20130230490-A1 PEG-Interferon Lambda 1 Conjugates NANOGEN PHARMACEUTICAL BIOTECHNOLOGY (VN) 2013-09-05 US disclosed
US-8454947-B1 PEG-interferon lambda 1 conjugates NANOGEN PHARMACEUTICAL BIOTECHNOLOGY (VN) 2013-06-04 US disclosed
US-8372833-B2 Urea derivative SHIONOGI & CO., LTD. (JP) 2013-02-12 US disclosed
US-20120095231-A1 UREA DERIVATIVE YANO TOSHISADA (JP) 2012-04-19 US disclosed
US-8088777-B2 Urea derivative SHIONOGI & CO., LTD. (JP) 2012-01-03 US disclosed
US-8084395-B2 4-aza indole derivatives and their use as fungicides SYNGENTA CROP PROTECTION, INC. (US) 2011-12-27 US disclosed
US-7919523-B2 Inhibitors of aspartyl protease VERTEX PHARMACEUTICALS, INC. (US) 2011-04-05 US disclosed
US-7919523-B2 Inhibitors of aspartyl protease VERTEX PHARMACEUTICALS, INC. (US) 2011-04-05 US disclosed
US-20100184598-A1 4-AZA INDOLE DERIVATIVES AND THEIR USE AS FUNGICIDES SYNGENTA PARTICIPATIONS AG (CH) 2010-07-22 US disclosed
US-20090203712-A1 Urea Derivative SHIONOGI &CO., LTD. 2009-08-13 US disclosed
US-20090042973-A1 Inhibitors of aspartyl protease VERTEX PHARMACEUTICALS INCORPORATED 2009-02-12 US disclosed
US-20090042973-A1 Inhibitors of aspartyl protease VERTEX PHARMACEUTICALS INCORPORATED 2009-02-12 US disclosed
US-7442718-B2 Inhibitors of aspartyl protease VERTEX PHARMACEUTICALS INCORPORATED (US) 2008-10-28 US disclosed
US-7442718-B2 Inhibitors of aspartyl protease VERTEX PHARMACEUTICALS INCORPORATED (US) 2008-10-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090042973-A1 Inhibitors of aspartyl protease SPINT2, DNPEP, PRSS1 MEN1 4418/4885KMT2A 864/4885EPHX1 2453/4885
US-20230144211-A1 ANTIFOLATE LINKER-DRUGS AND ANTIBODY-DRUG CONJUGATES DHFR, FOLR1, MTHFD2 MEN1 1545/4885KMT2A 1224/4885EPHX1 1281/4885
US-20130230490-A1 PEG-Interferon Lambda 1 Conjugates IFNG, IFNAR1, IGLV6-57 MEN1 3401/4885KMT2A 4197/4885EPHX1 3175/4885
US-20230226214-A1 BIFUNCTIONAL BRIDGING COMPOSITIONS FOR VIRAL TRANSDUCTION HAVCR2, FCGR3B, FCGR2A MEN1 1824/4885KMT2A 3875/4885EPHX1 4322/4885
US-20120095231-A1 UREA DERIVATIVE NPY5R, NPY1R, NPY2R MEN1 2951/4885KMT2A 3557/4885EPHX1 4596/4885
US-20200172575-A1 PEPTIDE COMPOUND AND APPLICATION THEREOF, AND COMPOSITION CONTAINING PEPTIDE COMPOUND KISS1R, VIP, NPY1R MEN1 268/4885KMT2A 3979/4885EPHX1 3986/4885
US-20090203712-A1 Urea Derivative NPY5R, NPY1R, NPY2R MEN1 2927/4885KMT2A 3489/4885EPHX1 4592/4885
US-20100184598-A1 4-AZA INDOLE DERIVATIVES AND THEIR USE AS FUNGICIDES IDO1, INMT, AZI2 MEN1 1241/4885KMT2A 957/4885EPHX1 1979/4885
US-20220119392-A1 ANTIFOLATE LINKER-DRUGS AND ANTIBODY-DRUG CONJUGATES DHFR, FOLR1, MTHFD2 MEN1 1545/4885KMT2A 1224/4885EPHX1 1281/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.