SCHEMBL2601602

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2601604	0.88	CRHBP (0.41)	CRHBPCRHR2HPRT1MAPTABCC1
	SCHEMBL10034250	0.88	CRHBP (0.41)	CRHBPCRHR2HPRT1MAPTABCC1
	SCHEMBL14460556	0.86	MAPT (0.47)	CRHBPCRHR2HPRT1MAPTMAOA
	SCHEMBL15860099	0.85	ALDH1A1 (0.51)	CRHBPCRHR2HPRT1MAPTMAOA
	SCHEMBL2601574	0.83	ALDH1A1 (0.51)	HPRT1MAPTMAOATDP1ALDH1A1
	SCHEMBL2816974	0.82	CRHBP (0.61)	CRHBPCRHR2HPRT1MAPTABCC1
	SCHEMBL14460561	0.81	MAPT (0.40)	CRHBPCRHR2HPRT1MAPTABCC1
	SCHEMBL15791110	0.81	TDP1 (0.53)	CRHBPCRHR2HPRT1MAPTABCC1
	SCHEMBL22155779	0.81	RAB9A (0.45)	HPRT1MAPTTDP1ALDH1A1NPC1
	SCHEMBL15906929	0.81	S100A4 (0.43)	HPRT1MAPTMAOATDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.