SCHEMBL26016243

SCHEMBL26016243

CC(C)(C)OC(=O)[C@@H](N)CCC(=O)NCCOCCOCCOCCN=[N+]=[N-]

nearest known ligand 0.37

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ LTA4H P09960 1/20 0.37
▸ CRBN Q96SW2 1/20 0.33
▸ PLK1 P53350 1/20 0.32
▸ MEN1 O00255 1/20 0.31
▸ KMT2A Q03164 1/20 0.31
▸ NOS1 P29475 2/20 0.31
▸ NOS3 P29474 1/20 0.31
▸ NOS2 P35228 1/20 0.31
▸ CA12 O43570 2/20 0.30
▸ CA1 P00915 2/20 0.30
▸ CA2 P00918 2/20 0.30
▸ CA4 P22748 2/20 0.30
▸ CA9 Q16790 2/20 0.30
▸ CA14 Q9ULX7 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26848393 0.99 LTA4H (0.38) LTA4HCRBNPLK1NOS1NOS3
SCHEMBL26028782 0.94 LTA4H (0.37) LTA4HPLK1NOS1NOS3NOS2
SCHEMBL26016247 0.88 MEN1 (0.34) CRBNMEN1KMT2A
SCHEMBL26848397 0.86 ALDH1A1 (0.33) CRBNMEN1KMT2A
SCHEMBL24906687 0.84 MEN1 (0.33) CRBNMEN1KMT2ACA12CA1
SCHEMBL26030117 0.84 MEN1 (0.33) CRBNMEN1KMT2ACA12CA1
SCHEMBL30346421 0.84 BCHE (0.38) MEN1KMT2A
SCHEMBL16049361 0.83 MEN1 (0.43) LTA4HPLK1MEN1KMT2ACA12
SCHEMBL22301077 0.83 LTA4H (0.41) LTA4HPLK1MEN1KMT2ACA12
SCHEMBL24811754 0.83 LTA4H (0.41) LTA4HPLK1MEN1KMT2ACA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230263898-A1 FOLATE RECEPTOR TARGETED NANOPARTICLE DRUG CONJUGATES AND USES THEREOF ELUCIDA ONCOLOGY, INC. 2023-08-24 — — US disclosed
US-20230241243-A1 CARRIER PARTICLE-DRUG CONJUGATES, SELF-IMMOLATIVE LINKERS, AND USES THEREOF ELUCIDA ONCOLOGY, INC. 2023-08-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230241243-A1 CARRIER PARTICLE-DRUG CONJUGATES, SELF-IMMOLATIVE LINKERS, AND USES THEREOF NDC1, KIFC1, SDCBP LTA4H 3377/4885CRBN 963/4885PLK1 32/4885
US-20230263898-A1 FOLATE RECEPTOR TARGETED NANOPARTICLE DRUG CONJUGATES AND USES THEREOF FOLR1, FOLR2, DHFR LTA4H 4310/4885CRBN 1939/4885PLK1 481/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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