SCHEMBL26030117

SCHEMBL26030117

CC(C)COC(=O)C(N)CCC(=O)NCCOCCOCCOCCN=[N+]=[N-]

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 1/20 0.33
▸ KMT2A Q03164 1/20 0.33
▸ CRBN Q96SW2 1/20 0.33
▸ ALDH1A1 P00352 1/20 0.32
▸ CA12 O43570 2/20 0.30
▸ CA1 P00915 2/20 0.30
▸ CA2 P00918 2/20 0.30
▸ CA4 P22748 2/20 0.30
▸ CA9 Q16790 2/20 0.30
▸ CA14 Q9ULX7 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24906687 1.00 MEN1 (0.33) MEN1KMT2ACRBNALDH1A1CA12
SCHEMBL26030157 0.94 ALDH1A1 (0.34) ALDH1A1
SCHEMBL26852355 0.92 TSHR (0.33) ALDH1A1
SCHEMBL26016243 0.84 LTA4H (0.37) MEN1KMT2ACRBNCA12CA1
SCHEMBL26133563 0.83 NOS3 (0.41) KMT2ACRBNCA12CA1CA2
SCHEMBL26133569 0.83 NOS3 (0.41) KMT2ACRBNCA12CA1CA2
SCHEMBL31297097 0.83 MEN1 (0.38) MEN1KMT2ACRBNCA12CA1
SCHEMBL26848393 0.83 LTA4H (0.38) CRBNALDH1A1
SCHEMBL30980666 0.82 CRBN (0.37) MEN1KMT2ACRBNALDH1A1CA12
SCHEMBL26502517 0.81 ALDH1A1 (0.32) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230263898-A1 FOLATE RECEPTOR TARGETED NANOPARTICLE DRUG CONJUGATES AND USES THEREOF ELUCIDA ONCOLOGY, INC. 2023-08-24 — — US disclosed
US-20230241243-A1 CARRIER PARTICLE-DRUG CONJUGATES, SELF-IMMOLATIVE LINKERS, AND USES THEREOF ELUCIDA ONCOLOGY, INC. 2023-08-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230241243-A1 CARRIER PARTICLE-DRUG CONJUGATES, SELF-IMMOLATIVE LINKERS, AND USES THEREOF NDC1, KIFC1, SDCBP MEN1 2314/4885KMT2A 4146/4885CRBN 963/4885
US-20230263898-A1 FOLATE RECEPTOR TARGETED NANOPARTICLE DRUG CONJUGATES AND USES THEREOF FOLR1, FOLR2, DHFR MEN1 3521/4885KMT2A 2800/4885CRBN 1939/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback