Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.46 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.42 |
| ▸ | KDM5A | P29375 | 1/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.42 |
| ▸ | THRA | P10827 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CAMK2A | Q9UQM7 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | ERCC1 | P07992 | 2/20 | 0.40 |
| ▸ | ERCC4 | Q92889 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11859884 | 0.87 | CA2 (0.67) | CA2LMNATHRATHRBALDH1A1 | |
| SCHEMBL16267698 | 0.86 | CA2 (0.47) | CA2LMNAMAPK1NLRP1ALDH1A1 | |
| SCHEMBL32678875 | 0.84 | LMNA (0.44) | CA2LMNAMAPK1NLRP1 | |
| SCHEMBL32678876 | 0.84 | LMNA (0.44) | CA2LMNAMAPK1NLRP1 | |
| SCHEMBL32678874 | 0.84 | LMNA (0.44) | CA2LMNAMAPK1NLRP1 | |
| SCHEMBL11103613 | 0.84 | CA2 (0.53) | CA2LMNADGAT1THRATHRB | |
| SCHEMBL510145 | 0.83 | ALDH1A1 (0.45) | CA2LMNAALDH1A1CAMK2AHPGD | |
| SCHEMBL31254084 | 0.83 | ALDH1A1 (0.45) | CA2LMNAALDH1A1CAMK2AHPGD | |
| SCHEMBL2602714 | 0.82 | LMNA (0.46) | LMNAMAPK1NLRP1KDM5AKDM4C | |
| SCHEMBL14093025 | 0.81 | TRPA1 (0.55) | CA2LMNAMAPK1ALDH1A1CAMK2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7109370-B2 | Substituted phenylketoenols | BAYER AKTIENGESELLSCHAFT (DE) | 2006-09-19 | — | — | US | disclosed |
| US-20050187111-A1 | Novel substituted phenylketoenols | HAGEMANN HERMANN (DE) | 2005-08-25 | — | — | US | disclosed |
| EP-1028963-B1 | NOVEL SUBSTITUTED PHENYL KETO ENOLS | BAYER CROPSCIENCE AG (DE) | 2005-06-15 | — | — | EP | disclosed |
| US-6900341-B2 | Substituted phenylketoenols | BAYER AKTIENGESELLSCHAFT (DE) | 2005-05-31 | — | — | US | disclosed |
| EP-1508560-A2 | Substituted Phenylketoenols | Bayer CropScience AG (DE) | 2005-02-23 | — | — | EP | disclosed |
| US-20040102327-A1 | Pesticides, herbicides; spiropyran-pyrroline-2-one deriva-tives | HAGEMANN HERMANN (DE) | 2004-05-27 | — | — | US | disclosed |
| US-6670488-B1 | N-(phenylacetyl)-4-amino-4-carboxyethyl-2-methyl -tetrahydropyran intermediate cyclizes to 3-(phenyl)-5,5-((2-ethyl)- ethylene oxyethyl)-pyrrolin-2-one-4-carboxylate herbicide | BAYER AKTIENGESELLSCHAFT (DE) | 2003-12-30 | — | — | US | disclosed |
| US-20030228984-A1 | Novel substituted phenylketoenols | HAGEMANN HERMANN (DE) | 2003-12-11 | — | — | US | disclosed |
| US-6608211-B1 | Pesticides and herbicides; well tolerated by plants | BAYER AKTIENGESELLSCHAFT (DE) | 2003-08-19 | — | — | US | disclosed |
| EP-1028963-A1 | NOVEL SUBSTITUTED PHENYL KETO ENOLS | BAYER AG (DE) | 2000-08-23 | — | — | EP | disclosed |
| WO-1999024437-A1 | NOVEL SUBSTITUTED PHENYL KETO ENOLS | BAYER AKTIENGESELLSCHAFT (DE) | 1999-05-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030228984-A1 | Novel substituted phenylketoenols | AKR1A1, AKR1B1, AKR1C1 | CA2 1660/4885LMNA 2230/4885MAPK1 613/4885 |
| US-20050187111-A1 | Novel substituted phenylketoenols | PDHX, AKR1A1, AKR1B1 | CA2 1850/4885LMNA 2051/4885MAPK1 1632/4885 |
| US-20040102327-A1 | Pesticides, herbicides; spiropyran-pyrroline-2-one deriva-tives | PDHA1, PDHA2, DDT | CA2 874/4885LMNA 2687/4885MAPK1 2290/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.