SCHEMBL260299

SCHEMBL260299

CCOC(=O)c1cccc(NC(N)=S)c1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.74
KMT2A Q03164 5/20 0.65
TSHR P16473 1/20 0.65
NPSR1 Q6W5P4 2/20 0.63
MAPT P10636 4/20 0.62
MEN1 O00255 4/20 0.62
MAPK1 P28482 3/20 0.62
LMNA P02545 2/20 0.62
RAB9A P51151 7/20 0.62
NPC1 O15118 6/20 0.62
SMN1; SMN2 Q16637 6/20 0.62
POLB P06746 2/20 0.62
CYP1A2 P05177 1/20 0.62
CYP2C9 P11712 1/20 0.62
HPGD P15428 1/20 0.62
CYP2C19 P33261 1/20 0.62
PKM P14618 1/20 0.62
HSD17B10 Q99714 1/20 0.60
CA12 O43570 1/20 0.58
CA1 P00915 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8123409 0.88 KMT2A (0.68) ALDH1A1KMT2ATSHRNPSR1MAPT
SCHEMBL5552521 0.86 SMN1; SMN2 (0.71) ALDH1A1KMT2ATSHRNPSR1MAPT
SCHEMBL8687140 0.86 KMT2A (0.65) ALDH1A1KMT2ATSHRNPSR1MAPT
SCHEMBL983433 0.85 ALDH1A1 (1.00) ALDH1A1KMT2AMAPTMEN1LMNA
SCHEMBL11756491 0.85 ALDH1A1 (0.72) ALDH1A1KMT2ATSHRNPSR1MAPT
SCHEMBL7808621 0.84 SMN1; SMN2 (0.70) ALDH1A1KMT2ATSHRNPSR1MAPT
SCHEMBL11655759 0.84 SMN1; SMN2 (0.80) ALDH1A1KMT2ATSHRNPSR1MAPT
SCHEMBL14096496 0.83 ALDH1A1 (0.70) ALDH1A1KMT2ANPSR1MAPTMEN1
SCHEMBL14266467 0.82 KMT2A (0.77) ALDH1A1KMT2ATSHRNPSR1MAPT
SCHEMBL1615839 0.82 SMN1; SMN2 (0.73) ALDH1A1KMT2ATSHRNPSR1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 417 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240225002-A1 FUNGICIDAL COMPOSITION CONTAINING OXADIAZOLE COMPOUNDS PI INDUSTRIES LTD. (IN) 2024-07-11 US claimed
US-11839214-B2 Fungicidal mixture comprising substituted pyridines BASF SE (DE) 2023-12-12 US claimed
US-20230159561-A1 HETEROCYCLE-SUBSTITUTED BICYCLIC AZOLE PESTICIDES FMC CORP (US) 2023-05-25 US claimed
EP-4105209-A2 HETEROCYCLE-SUBSTITUTED BICYCLIC AZOLE PESTICIDES FMC Corporation (US) 2022-12-21 EP claimed
EP-3978504-A1 CHIRAL 2,3-DIHYDROTHIAZOLO[3,2-A]PYRIMIDINE DERIVATIVES FOR COMBATING ANIMAL PESTS BASF SE (DE) 2022-04-06 EP claimed
US-20220046925-A1 METHOD OF CONTROLLING PESTS BY SEED TREATMENT APPLICATION OF A MESOIONIC COMPOUND OR MIXTURE THEREOF BASF SE (DE) 2022-02-17 US claimed
EP-3601298-B1 PROCESS FOR PREPARING CHIRAL 2,3-DIHYDROTHIAZOLO[3,2-A]PYRIMIDIN-4-IUM COMPOUNDS BASF SE (DE) 2021-12-01 EP claimed
US-20210355139-A1 Pyrimidinium Compounds and Their Mixtures for Combating Animal Pests BASF SE (DE) 2021-11-18 US claimed
US-11076600-B2 Mixtures of cis-jasmone and bacillus amyloliquefaciens BASF SE (DE) 2021-08-03 US claimed
US-20210127674-A1 FUNGICIDAL MIXTURE COMPRISING SUBSTITUTED PYRIDINES BASF SE (DE) 2021-05-06 US claimed
WO-2017153200-A1 FUNGICIDAL MIXTURES III COMPRISING STROBILURIN-TYPE FUNGICIDES BASF SE (DE) 2017-09-14 WO claimed
US-20170238554-A1 Method and Pesticidal Mixtures for Controlling Pentatomidae Pests BASF CORPORATION 2017-08-24 US claimed
EP-3206490-A1 METHOD AND PESTICIDAL MIXTURES FOR CONTROLLING PENTATOMIDAE PESTS BASF SE (DE) 2017-08-23 EP claimed
EP-3205208-A1 MIXTURES AND COMPOSITIONS COMPRISING PAENIBACILLUS STRAINS OR FUSARICIDINS AND CHEMICAL PESTICIDES BASF SE (DE) 2017-08-16 EP claimed
US-20170174707-A1 HETEROCYCLE-SUBSTITUTED BICYCLIC AZOLE PESTICIDES FMC CORPORATION 2017-06-22 US claimed
WO-2017093163-A1 MIXTURES OF CIS-JASMONE AND BACILLUS AMYLOLIQUEFACIENS BASF SE (DE) 2017-06-08 WO claimed
WO-2016144351-A1 HETEROCYCLE-SUBSTITUTED BICYCLIC AZOLE PESTICIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2016-09-15 WO claimed
EP-3044220-A1 HETEROCYCLE-SUBSTITUTED BICYCLIC AZOLE PESTICIDES E. I. du Pont de Nemours and Company (US) 2016-07-20 EP claimed
WO-2016059240-A1 METHOD AND PESTICIDAL MIXTURES FOR CONTROLLING PENTATOMIDAE PESTS BASF SE (DE) 2016-04-21 WO claimed
WO-2015038503-A1 HETEROCYCLE-SUBSTITUTED BICYCLIC AZOLE PESTICIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2015-03-19 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230159561-A1 HETEROCYCLE-SUBSTITUTED BICYCLIC AZOLE PESTICIDES CYP4X1, DDT, CHRM1 ALDH1A1 2441/4885KMT2A 2497/4885TSHR 1382/4885
US-11076600-B2 Mixtures of cis-jasmone and bacillus amyloliquefaciens BAX, FASN, BAK1 ALDH1A1 4217/4885KMT2A 4623/4885TSHR 3364/4885
US-11839214-B2 Fungicidal mixture comprising substituted pyridines ME1, DPM1, TH ALDH1A1 913/4885KMT2A 2611/4885TSHR 4645/4885
US-20210127674-A1 FUNGICIDAL MIXTURE COMPRISING SUBSTITUTED PYRIDINES ME1, DPM1, TH ALDH1A1 913/4885KMT2A 2611/4885TSHR 4645/4885
US-20240225002-A1 FUNGICIDAL COMPOSITION CONTAINING OXADIAZOLE COMPOUNDS OXA1L, NOX1, NOX3 ALDH1A1 63/4885KMT2A 3280/4885TSHR 3698/4885
US-20220046925-A1 METHOD OF CONTROLLING PESTS BY SEED TREATMENT APPLICATION OF A MESOIONIC COMPOUND OR MIXTURE THEREOF MANBA, CMA1, MTX1 ALDH1A1 3619/4885KMT2A 2080/4885TSHR 3331/4885
US-20210355139-A1 Pyrimidinium Compounds and Their Mixtures for Combating Animal Pests THOP1, NIT2, DDT ALDH1A1 1846/4885KMT2A 3738/4885TSHR 861/4885
US-20170174707-A1 HETEROCYCLE-SUBSTITUTED BICYCLIC AZOLE PESTICIDES CYP4X1, DDT, CHRM1 ALDH1A1 2441/4885KMT2A 2497/4885TSHR 1382/4885
US-20170238554-A1 Method and Pesticidal Mixtures for Controlling Pentatomidae Pests CASP9, CASP6, CASP14 ALDH1A1 3243/4885KMT2A 3269/4885TSHR 2610/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.