Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | BMP4 | P12644 | 3/20 | 0.53 |
| ▸ | BMPR1B | O00238 | 2/20 | 0.52 |
| ▸ | KDR | P35968 | 2/20 | 0.52 |
| ▸ | BMPR1A | P36894 | 2/20 | 0.52 |
| ▸ | ACVRL1 | P37023 | 2/20 | 0.52 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.52 |
| ▸ | ACVR1B | P36896 | 1/20 | 0.52 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.52 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.52 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.47 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.47 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2603412 | 0.90 | CYP11B2 (0.46) | KDM4EALDH1A1SMN1; SMN2HPGDBMP4 | |
| SCHEMBL2758623 | 0.86 | RAB9A (0.55) | KDM4EALDH1A1SMN1; SMN2HPGDACVR1 | |
| SCHEMBL4875259 | 0.85 | ALOX15 (0.56) | KDM4EALDH1A1SMN1; SMN2HPGDBMP4 | |
| SCHEMBL30251801 | 0.81 | BMP4 (0.61) | KDM4EALDH1A1HPGDBMP4BMPR1B | |
| SCHEMBL7665284 | 0.81 | BMP4 (0.61) | KDM4EALDH1A1HPGDBMP4BMPR1B | |
| SCHEMBL2758627 | 0.80 | NPC1 (0.44) | KDM4EALDH1A1SMN1; SMN2HPGDACVR1 | |
| SCHEMBL4883102 | 0.78 | RAB9A (0.56) | KDM4EALDH1A1SMN1; SMN2HPGDKDR | |
| SCHEMBL10909733 | 0.77 | TSHR (0.74) | KDM4EALDH1A1SMN1; SMN2HPGDKDR | |
| SCHEMBL4875222 | 0.77 | TSHR (0.74) | KDM4EALDH1A1SMN1; SMN2HPGDKDR | |
| SCHEMBL1180905 | 0.76 | KDM4E (0.72) | KDM4EALDH1A1SMN1; SMN2HPGDPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080015193-A1 | Certain azoles exhibiting ATP-utilizing enzyme inhibitory activity, compositions, and uses thereof | AGRIUS GROUP, LLC. | 2008-01-17 | — | — | US | claimed |
| US-9644099-B2 | Violet laser excitable dyes and their method of use | Life Technologies Corporation (US) | 2017-05-09 | — | — | US | disclosed |
| US-20160355682-A1 | VIOLET LASER EXCITABLE DYES AND THEIR METHOD OF USE | Life Technologies Corporation | 2016-12-08 | — | — | US | disclosed |
| US-20150050685-A1 | VIOLET LASER EXCITABLE DYES AND THEIR METHOD OF USE | LIFE TECHNOLOGIES CORP (US) | 2015-02-19 | — | — | US | disclosed |
| US-8822695-B2 | Violet laser excitable dyes and their method of use | Life Technologies Corporation (US) | 2014-09-02 | — | — | US | disclosed |
| US-20130273569-A1 | VIOLET LASER EXCITABLE DYES AND THEIR METHOD OF USE | LIFE TECHNOLOGIES CORP (US) | 2013-10-17 | — | — | US | disclosed |
| US-8415477-B2 | Violet laser excitable dyes and their method of use | Life Technologies Corporation (US) | 2013-04-09 | — | — | US | disclosed |
| US-8158801-B2 | Violet laser excitable dyes and their method of use | Life Technologies Corporation (US) | 2012-04-17 | — | — | US | disclosed |
| US-8158801-B2 | Violet laser excitable dyes and their method of use | Life Technologies Corporation (US) | 2012-04-17 | — | — | US | disclosed |
| US-20120004397-A1 | VIOLET LASER EXCITABLE DYES AND THEIR METHOD OF USE | Life Technologies Corporation (US) | 2012-01-05 | — | — | US | disclosed |
| US-20080015193-A1 | Certain azoles exhibiting ATP-utilizing enzyme inhibitory activity, compositions, and uses thereof | AGRIUS GROUP, LLC. | 2008-01-17 | — | — | US | disclosed |
| WO-2007149395-A2 | 2,5-SUBSTITUTED OXAZOLE DERIVATIVES AS PROTEIN KINASE INHIBITORS FOR THE TREATMENT OF CANCER | AMPHORA DISCOVERY CORPORATION (US) | 2007-12-27 | — | — | WO | disclosed |
| US-20070077549-A1 | VIOLET LASER EXCITABLE DYES AND THEIR METHOD OF USE | INVITROGEN CORPORATION (US) | 2007-04-05 | — | — | US | disclosed |
| US-20070077549-A1 | VIOLET LASER EXCITABLE DYES AND THEIR METHOD OF USE | INVITROGEN CORPORATION (US) | 2007-04-05 | — | — | US | disclosed |
| WO-2007038659-A1 | VIOLET LASER EXCITABLE DYES AND THEIR METHOD OF USE | INVITROGEN CORPORATION (US) | 2007-04-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130273569-A1 | VIOLET LASER EXCITABLE DYES AND THEIR METHOD OF USE | KLK3, ALDH1A2, SPR | KDM4E 468/4885ALDH1A1 145/4885SMN1; SMN2 4284/4885 |
| US-20070077549-A1 | VIOLET LASER EXCITABLE DYES AND THEIR METHOD OF USE | KLK3, ALDH1A2, SPR | KDM4E 468/4885ALDH1A1 145/4885SMN1; SMN2 4284/4885 |
| US-20120004397-A1 | VIOLET LASER EXCITABLE DYES AND THEIR METHOD OF USE | KLK3, ALDH1A2, SPR | KDM4E 468/4885ALDH1A1 145/4885SMN1; SMN2 4284/4885 |
| US-20080015193-A1 | Certain azoles exhibiting ATP-utilizing enzyme inhibitory activity, compositions, and uses thereof | ATP5ME, ATP5MG, ATP5MK | KDM4E 2869/4885ALDH1A1 404/4885SMN1; SMN2 4756/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.