Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 10/20 | 0.47 |
| ▸ | TSHR | P16473 | 9/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.47 |
| ▸ | CTSK | P43235 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | PREP | P48147 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2605317 | 0.85 | SLC6A9 (0.57) | CYP3A4TSHRCYP2C9ALDH1A1CYP2C19 | |
| SCHEMBL2605312 | 0.76 | CTSK (0.48) | CYP3A4TSHRCYP2C9ALDH1A1CYP2C19 | |
| SCHEMBL12235290 | 0.74 | ATM (0.50) | CYP3A4TSHRCYP2C9ALDH1A1CYP2C19 | |
| SCHEMBL22698689 | 0.74 | ATM (0.56) | CYP3A4TSHRCYP2C9ALDH1A1CYP2C19 | |
| SCHEMBL8041576 | 0.73 | ATM (0.64) | ALDH1A1CTSKATM | |
| SCHEMBL308291 | 0.73 | ATM (0.64) | CYP3A4TSHRALDH1A1CTSKATM | |
| SCHEMBL25416211 | 0.73 | SMN1; SMN2 (0.46) | CYP3A4CYP2C9CYP2C19MEN1KMT2A | |
| SCHEMBL25416278 | 0.72 | ATM (0.53) | CYP3A4TSHRCYP2C9ALDH1A1CYP2C19 | |
| SCHEMBL22233607 | 0.72 | ITGB3 (0.51) | CYP3A4TSHRCYP2C9ALDH1A1CYP2C19 | |
| SCHEMBL19701701 | 0.72 | ITGB3 (0.51) | CYP3A4TSHRCYP2C9ALDH1A1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120094995-A1 | 2-AZA-BICYCLO[2.2.1]HEPTANE COMPOUNDS AND USES THEREOF | ASTRAZENECA AB (SE) | 2012-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120094995-A1 | 2-AZA-BICYCLO[2.2.1]HEPTANE COMPOUNDS AND USES THEREOF | SLC1A2, B4GALT1, SLC6A1 | CYP3A4 838/4885TSHR 3969/4885CYP2C9 946/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.