Epicoprosterol

Epicoprosterol

SCHEMBL2608072

CC(C)CCCC(C)C1CCC2C3CCC4CC(O)CCC4(C)C3CCC12C

nearest known ligand 0.78

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ OSBP P22059 1/20 0.78
▸ OSBP2 Q969R2 1/20 0.78
▸ CYP2C19 P33261 2/20 0.76
▸ CYP2D6 P10635 1/20 0.76
▸ ST6GAL1 P15907 2/20 0.75
▸ INPP5D Q92835 1/20 0.74
▸ GPBAR1 Q8TDU6 5/20 0.72
▸ CASP7 P55210 3/20 0.72
▸ HIF1A Q16665 3/20 0.72
▸ TP53 P04637 2/20 0.72
▸ MAPK1 P28482 2/20 0.72
▸ HSD17B10 Q99714 2/20 0.72
▸ BLM P54132 2/20 0.72
▸ TDP1 Q9NUW8 2/20 0.72
▸ VDR P11473 2/20 0.72
▸ USP2 O75604 2/20 0.72
▸ LMNA P02545 2/20 0.72
▸ CYP3A4 P08684 2/20 0.72
▸ MDM4 O15151 1/20 0.72
▸ MAPT P10636 1/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Epicoprosterol SCHEMBL11375007 1.00 OSBP (0.78) OSBPOSBP2CYP2C19CYP2D6ST6GAL1
Epicoprosterol SCHEMBL10066473 1.00 OSBP (0.78) OSBPOSBP2CYP2C19CYP2D6ST6GAL1
Epicoprosterol SCHEMBL18724866 1.00 OSBP (0.78) OSBPOSBP2CYP2C19CYP2D6ST6GAL1
Epicoprosterol SCHEMBL9906585 1.00 OSBP (0.78) OSBPOSBP2CYP2C19CYP2D6ST6GAL1
Epicoprosterol SCHEMBL24632942 1.00 OSBP (0.78) OSBPOSBP2CYP2C19CYP2D6ST6GAL1
Epicoprosterol SCHEMBL12549295 1.00 OSBP (0.78) OSBPOSBP2CYP2C19CYP2D6ST6GAL1
Epicoprosterol SCHEMBL25267973 1.00 OSBP (0.78) OSBPOSBP2CYP2C19CYP2D6ST6GAL1
Epicoprosterol SCHEMBL12214992 1.00 OSBP (0.78) OSBPOSBP2CYP2C19CYP2D6ST6GAL1
Epicoprosterol SCHEMBL21000320 1.00 OSBP (0.78) OSBPOSBP2CYP2C19CYP2D6ST6GAL1
Epicoprosterol SCHEMBL22018677 1.00 OSBP (0.78) OSBPOSBP2CYP2C19CYP2D6ST6GAL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250333479-A1 NOVEL FUSION MOLECULES AND USES THEREOF FOUNDATION MEDICINE, INC. (US) 2025-10-30 — — US disclosed
US-20250333480-A1 FUSION MOLECULES AND USES THEREOF FOUNDATION MEDICINE, INC. (US) 2025-10-30 — — US disclosed
US-20240293551-A1 USE OF ST-TYPE LIPID COMPOUNDS IN PREPARATION OF NUCLEIC ACID DELIVERY REAGENT AND RELATED PRODUCT BEIJING BAISHIHEKANG PHARMACEUTICAL TECHNOLOGY (BSJPHARMA) CO., LTD (CN) 2024-09-05 — — US disclosed
EP-4378483-A1 USE OF ST-TYPE LIPID COMPOUNDS IN PREPARATION OF NUCLEIC ACID DELIVERY REAGENT AND RELATED PRODUCT Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences (CN) 2024-06-05 — — EP disclosed
EP-3529257-B1 OXYSTEROLS AND METHODS OF USE THEREOF SAGE THERAPEUTICS INC (US) 2023-05-10 — — EP disclosed
US-20210253872-A1 METHOD FOR ESTABLISHING A FOULING RELEASE COATING SYSTEM HEMPEL A/S (DK) 2021-08-19 — — US disclosed
US-10690651-B2 Small molecule metabolites for the diagnosis of bacterial vaginosis and assessment of disease risk FRED HUTCHINSON CANCER RESEARCH CENTER (US) 2020-06-23 — — US disclosed
EP-3443054-B1 PROCESS FOR PRODUCING A COMBUSTIBLE PRODUCT INDUSTRIAL CHEMICALS GROUP LTD (GB) 2020-01-29 — — EP disclosed
US-20190078032-A1 PROCESS FOR PRODUCING A COMBUSTIBLE PRODUCT INDUSTRIAL CHEMICALS GROUP LIMITED (GB) 2019-03-14 — — US disclosed
EP-3231856-A1 COMBUSTIBLE PRODUCT Industrial Chemicals Group Limited (GB) 2017-10-18 — — EP disclosed
WO-2009104649-A1 SYNTHETIC GLYCOLIPID-CONTAINING LIPOSOMES 片山化学工業株式会社 (JP) 2009-08-27 — — WO disclosed
US-7544863-B2 Transgenic plants containing altered levels of steroid compounds MONSANTO TECHNOLOGY LLC (US) 2009-06-09 — — US disclosed
US-20090029949-A1 GPCR Ligands Identified by Computational Modeling NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR 2009-01-29 — — US disclosed
US-20080102405-A1 Nitrogen-containing organic compound, resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. 2008-05-01 — — US disclosed
US-20080064795-A1 MATERIALS FREE OF ENDOCRINE DISRUPTIVE ACTIVITY BITTNER GEORGE 2008-03-13 — — US disclosed
US-7303760-B2 Method for treating multi-drug resistant tumors ALZA CORPORATION (US) 2007-12-04 — — US disclosed
US-7276248-B2 Conjugate having a cleavable linkage for use in a liposome ALZA CORPORATION (US) 2007-10-02 — — US disclosed
US-20070122750-A1 Salt suitable for an acid generator and a chemically amplified resist composition containing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-05-31 — — US disclosed
US-20070122750-A1 Salt suitable for an acid generator and a chemically amplified resist composition containing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-05-31 — — US disclosed
US-20070122750-A1 Salt suitable for an acid generator and a chemically amplified resist composition containing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-05-31 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080102405-A1 Nitrogen-containing organic compound, resist composition and patterning process MDM4, MUS81, NOP2 OSBP 923/4885OSBP2 982/4885CYP2C19 1742/4885
US-20240293551-A1 USE OF ST-TYPE LIPID COMPOUNDS IN PREPARATION OF NUCLEIC ACID DELIVERY REAGENT AND RELATED PRODUCT POLRMT, LIPC, POLM OSBP 718/4885OSBP2 1512/4885CYP2C19 2589/4885
US-20250333479-A1 NOVEL FUSION MOLECULES AND USES THEREOF RPS27A, CD2BP2, FGB OSBP 2427/4885OSBP2 906/4885CYP2C19 4872/4885
US-20070122750-A1 Salt suitable for an acid generator and a chemically amplified resist composition containing the same HCN3, NHERF1, HCN4 OSBP 2292/4885OSBP2 2829/4885CYP2C19 951/4885
US-20090029949-A1 GPCR Ligands Identified by Computational Modeling LPAR3, LPAR2, LPAR1 OSBP 520/4885OSBP2 397/4885CYP2C19 4347/4885
US-20250333480-A1 FUSION MOLECULES AND USES THEREOF RPS27A, CD2BP2, FGB OSBP 2384/4885OSBP2 987/4885CYP2C19 4869/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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