Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 6/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.30 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.30 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL548987 | 0.84 | TUBB1 (0.41) | PTGS2PTGS1CD274 | |
| SCHEMBL3219578 | 0.80 | CD274 (0.30) | CD274 | |
| SCHEMBL2608090 | 0.77 | PTGS2 (0.38) | PTGS2PTGS1CD274AKR1C3AKR1C2 | |
| SCHEMBL17356558 | 0.72 | AKR1C3 (0.35) | PTGS2PTGS1AKR1C3AKR1C2 | |
| SCHEMBL2608091 | 0.71 | PTGS2 (0.39) | PTGS2PTGS1AKR1C3AKR1C2 | |
| SCHEMBL30498972 | 0.71 | GPR84 (0.36) | — | |
| SCHEMBL17359237 | 0.71 | AKR1C3 (0.34) | PTGS2PTGS1AKR1C3AKR1C2 | |
| SCHEMBL16038106 | 0.68 | CHKA (0.34) | AKR1C3 | |
| SCHEMBL2626383 | 0.68 | TUBB1 (0.41) | PTGS2PTGS1CD274 | |
| SCHEMBL378747 | 0.66 | ACHE (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8263798-B2 | Optically active quaternary ammonium salt having axial asymmetry, and method for producing alpha-amino acid and derivative thereof by using the same | NAGASE & CO., LTD. (JP) | 2012-09-11 | — | — | US | disclosed |
| US-8252952-B2 | Optically active quaternary ammonium salt having axial asymmetry, and method for producing alpha-amino acid and derivative thereof by using the same | NAGASE & CO., LTD. (JP) | 2012-08-28 | — | — | US | disclosed |
| US-20120108846-A1 | OPTICALLY ACTIVE QUATERNARY AMMONIUM SALT HAVING AXIAL ASYMMETRY, AND METHOD FOR PRODUCING ALPHA-AMINO ACID AND DERIVATIVE THEREOF BY USING THE SAME | NAGASE & CO., LTD. (JP) | 2012-05-03 | — | — | US | disclosed |
| US-20120101310-A1 | OPTICALLY ACTIVE QUATERNARY AMMONIUM SALT HAVING AXIAL ASYMMETRY, AND METHOD FOR PRODUCING ALPHA-AMINO ACID AND DERIVATIVE THEREOF BY USING THE SAME | NAGASE & CO., LTD. (JP) | 2012-04-26 | — | — | US | disclosed |
| US-20120095252-A1 | OPTICALLY ACTIVE QUATERNARY AMMONIUM SALT HAVING AXIAL ASYMMETRY, AND METHOD FOR PRODUCING ALPHA-AMINO ACID AND DERIVATIVE THEREOF BY USING THE SAME | NAGASE & CO., LTD. (JP) | 2012-04-19 | — | — | US | disclosed |
| US-20120095218-A1 | OPTICALLY ACTIVE QUATERNARY AMMONIUM SALT HAVING AXIAL ASYMMETRY, AND METHOD FOR PRODUCING ALPHA-AMINO ACID AND DERIVATIVE THEREOF BY USING THE SAME | NAGASE & CO., LTD. (JP) | 2012-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120108846-A1 | OPTICALLY ACTIVE QUATERNARY AMMONIUM SALT HAVING AXIAL ASYMMETRY, AND METHOD FOR PRODUCING ALPHA-AMINO ACID AND DERIVATIVE THEREOF BY USING THE SAME | AADAT, BCAT1, BCAT2 | PTGS2 4706/4885PTGS1 4703/4885CD274 4570/4885 |
| US-20120095252-A1 | OPTICALLY ACTIVE QUATERNARY AMMONIUM SALT HAVING AXIAL ASYMMETRY, AND METHOD FOR PRODUCING ALPHA-AMINO ACID AND DERIVATIVE THEREOF BY USING THE SAME | AADAT, BCAT1, BCAT2 | PTGS2 4706/4885PTGS1 4703/4885CD274 4570/4885 |
| US-20120095218-A1 | OPTICALLY ACTIVE QUATERNARY AMMONIUM SALT HAVING AXIAL ASYMMETRY, AND METHOD FOR PRODUCING ALPHA-AMINO ACID AND DERIVATIVE THEREOF BY USING THE SAME | AADAT, BCAT1, BCAT2 | PTGS2 4706/4885PTGS1 4703/4885CD274 4570/4885 |
| US-20120101310-A1 | OPTICALLY ACTIVE QUATERNARY AMMONIUM SALT HAVING AXIAL ASYMMETRY, AND METHOD FOR PRODUCING ALPHA-AMINO ACID AND DERIVATIVE THEREOF BY USING THE SAME | AADAT, BCAT1, BCAT2 | PTGS2 4706/4885PTGS1 4703/4885CD274 4570/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.