Sugi Predict

Sugi Predict / Compounds / SCHEMBL261067

SCHEMBL261067

SCHEMBL261067

O=C(O)c1n[nH]c2cc(Br)ccc12

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ IDO1 P14902 1/20 0.62
▸ PDPK1 O15530 2/20 0.56
▸ JAK2 O60674 2/20 0.56
▸ DYRK1A Q13627 5/20 0.55
▸ GSK3B P49841 1/20 0.50
▸ PRKAG1 P54619 8/20 0.45
▸ PRKAA1 Q13131 8/20 0.45
▸ PRKAB1 Q9Y478 8/20 0.45
▸ PRKAB2 O43741 7/20 0.45
▸ PRKAA2 P54646 7/20 0.45
▸ PRKAG3 Q9UGI9 7/20 0.45
▸ PRKAG2 Q9UGJ0 7/20 0.45
▸ HAO1 Q9UJM8 1/20 0.43
▸ DCLK1 O15075 1/20 0.42
▸ PRKD3 O94806 1/20 0.42
▸ MAP4K4 O95819 1/20 0.42
▸ CHEK2 O96017 1/20 0.42
▸ CSF1R P07333 1/20 0.42
▸ FER P16591 1/20 0.42
▸ CDK2 P24941 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30075258 1.00 IDO1 (0.62) IDO1PDPK1JAK2DYRK1AGSK3B
SCHEMBL260615 0.86 PDPK1 (0.61) IDO1PDPK1JAK2DYRK1AGSK3B
SCHEMBL19208914 0.85 JAK2 (0.59) IDO1PDPK1JAK2DYRK1AGSK3B
SCHEMBL30301502 0.85 DYRK1A (0.61) IDO1PDPK1JAK2DYRK1AGSK3B
SCHEMBL15077318 0.85 DYRK1A (0.61) IDO1PDPK1JAK2DYRK1AGSK3B
SCHEMBL30258217 0.81 KDM4E (0.63) IDO1PDPK1JAK2DYRK1AGSK3B
SCHEMBL21811353 0.81 IDO1 (0.64) IDO1PDPK1JAK2DYRK1AGSK3B
SCHEMBL29871192 0.81 IDO1 (0.64) IDO1PDPK1JAK2DYRK1AGSK3B
SCHEMBL11970499 0.81 JAK1 (0.54) IDO1PDPK1JAK2DYRK1AGSK3B
SCHEMBL498163 0.81 KDM4E (0.63) IDO1PDPK1JAK2DYRK1AGSK3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 273 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-211226714-U Wastewater treatment device for 6-bromoindazole-3-formic acid preparation process 南京道尔顿化学技术有限公司 2020-08-11 — — CN claimed
CN-110357323-A A kind of wastewater treatment equipment of 6- bromo-indazole -3- formic acid preparation process 南京道尔顿化学技术有限公司 2019-10-22 — — CN claimed
EP-1670787-A4 CYTOKINE INHIBITORS KEMIA INC (US) 2009-04-22 — — EP claimed
CN-1878769-A Cytokine inhibitors KEMIA INC (US) 2006-12-13 — — CN claimed
US-20060135589-A1 1h-Indazole-3-carboxamide compounds as cyclin dependent kinase (cdk) inhibitors ASTEX TECHNOLOGY, INC. (GB) 2006-06-22 — — US claimed
EP-1670787-A2 CYTOKINE INHIBITORS Kemia, INC. (US) 2006-06-21 — — EP claimed
JP-2006500348-A — — 2006-01-05 — — JP claimed
EP-1534685-A1 1H-INDAZOLE-3-CARBOXAMIDE COMPOUNDS AS CYCLIN DEPENDENT KINASES (CDK) INHIBITORS Astex Technology Limited (GB) 2005-06-01 — — EP claimed
US-20050107399-A1 Cytokine inhibitors KEMIA, INC. 2005-05-19 — — US claimed
WO-2005023761-A2 CYTOKINE INHIBITORS KEMIA, INC. (US) 2005-03-17 — — WO claimed
WO-2004014864-A1 1H-INDAZOLE-3-CARBOXAMIDE COMPOUNDS AS CYCLIN DEPENDENT KINASES (CDK) INHIBITORS ASTEX TECHNOLOGY LIMITED (GB) 2004-02-19 — — WO claimed
US-12637426-B2 1-cyano-pyrrolidine compounds as USP30 inhibitors MISSION THERAPEUTICS LIMITED (GB) 2026-05-26 — — US disclosed
EP-3870583-B1 SUBSTITUTED INDOLE AND INDAZOLE COMPOUNDS BRISTOL MYERS SQUIBB CO (US) 2026-04-22 — — EP disclosed
US-12577228-B2 Dihydrocyclopenta-isoquinoline-sulfonamide derivatives compounds UCB Biopharma SRL (BE) 2026-03-17 — — US disclosed
EP-4081296-B1 DIHYDROCYCLOPENTA-ISOQUINOLINE-SULFONAMIDE DERIVATIVES COMPOUNDS UCB Biopharma SRL (BE) 2026-02-11 — — EP disclosed
US-20050107399-A1 Cytokine inhibitors KEMIA, INC. 2005-05-19 — — US disclosed
WO-2005023761-A2 CYTOKINE INHIBITORS KEMIA, INC. (US) 2005-03-17 — — WO disclosed
US-20040132790-A1 Indazoles, benzothiazoles, and benzoisothiazoles, and preparation and uses thereof MEMORY PHARMACEUTICALS CORPORATION 2004-07-08 — — US disclosed
WO-2004029050-A1 INDAZOLES, BENZOTHIAZOLES, AND BENZOISOTHIAZOLES, AND PREPARATION AND USES THEREOF MEMORY PHARMACEUTICALS CORPORATION (US) 2004-04-08 — — WO disclosed
WO-2004014864-A1 1H-INDAZOLE-3-CARBOXAMIDE COMPOUNDS AS CYCLIN DEPENDENT KINASES (CDK) INHIBITORS ASTEX TECHNOLOGY LIMITED (GB) 2004-02-19 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050107399-A1 Cytokine inhibitors TNF, IL1RN, IL1A IDO1 229/4885PDPK1 2114/4885JAK2 47/4885
US-20040132790-A1 Indazoles, benzothiazoles, and benzoisothiazoles, and preparation and uses thereof CHRNA5, CHRNA7, CHRNA3 IDO1 311/4885PDPK1 1949/4885JAK2 2278/4885
US-12577228-B2 Dihydrocyclopenta-isoquinoline-sulfonamide derivatives compounds FCGR2A, FCER2, FCGR1A IDO1 205/4885PDPK1 3124/4885JAK2 958/4885
US-12637426-B2 1-cyano-pyrrolidine compounds as USP30 inhibitors USP30, USP1, USP10 IDO1 1728/4885PDPK1 2268/4885JAK2 1857/4885
US-20060135589-A1 1h-Indazole-3-carboxamide compounds as cyclin dependent kinase (cdk) inhibitors CCNC, CDK1, CDK7 IDO1 1336/4885PDPK1 2462/4885JAK2 197/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.